Is Obstructive Sleep Apnea Associated with Higher Covid-19 Severity?

被引：0
|
作者：
Zacarias, Laila Candida [1 ]
Torres, Danielle Mesquita [2 ]
Magalhaes, Samir Camara [2 ,3 ]
Sobreira-Neto, Manoel Alves [4 ]
Leite, Camila Ferreira [1 ,5 ]
机构：
[1] Univ Fed Ceara, Grad Program Cardiovasc Sci, Fortaleza, CE, Brazil
[2] Hosp Geral Fortaleza, Dept Neurol, Fortaleza, CE, Brazil
[3] Univ Fortaleza, Fac Med, Fortaleza, CE, Brazil
[4] Univ Fed Ceara, Dept Clin Med, Fortaleza, CE, Brazil
[5] Univ Fed Ceara, Masters Program Physiotherapy & Functioning, Fortaleza, CE, Brazil
来源：
SLEEP SCIENCE | 2024年 / 17卷 / 03期
关键词：
COVID-19; obstructive sleep apnea; sleep; polygraphy; OUTCOMES; RISK;
D O I：
10.1055/s-0044-1782166
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Objective To investigate the associations between obstructive sleep apnea (OSA) and coronavirus disease 2019 (COVID-19) severity. Methods Twelve individuals hospitalized in a Brazilian tertiary hospital diagnosed with COVID-19 by reverse transcriptase-polymerase chain reaction (RT-PCR) underwent respiratory polygraphy. Results Polygraphic records identified seven participants without obstructive sleep apnea (OSA) (OSA-) and five with OSA (OSA + ). The OSA+ group presented worse peripheral oxygen saturation (77.6% +/- 7.89%) than the OSA- group (84.4% +/- 2.57%) ( p = 0.041). Additionally, the OSA+ group showed greater COVID-19 severity (100%) than the OSA- group (28.57%) ( p = 0.013) and required longer oxygen therapy ( p = 0.038), but without difference in the length of hospitalization. The OSA+ group also presented higher rates of platelets ( p = 0.008) and D-dimer (1,443 +/- 897) than the OSA- group (648 +/- 263 ng/mL) ( p = 0.019). Conclusion Obstructive sleep apnea in individuals hospitalized due to COVID-19 was associated with higher COVID-19 severity, worse peripheral oxygen saturation, longer oxygen therapy time, and higher platelet and D-dimer rates.
引用
收藏
页码：e304 / e309
页数：6
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