Long-term noise exposure and cause-specific mortality in chronic respiratory diseases, considering the modifying effect of air pollution

被引：0

作者：

Zhang, Hehua ^{[1
,2
]}

Ye, Rui ^{[3
]}

Yang, Honghao ^{[2
,4
]}

Liu, Yashu ^{[2
,4
]}

Zhao, Li ^{[3
]}

Zhao, Yuhong ^{[2
,4
]}

Chen, Liangkai ^{[5
]}

Shan, Lishen ^{[6
]}

Xia, Yang ^{[2
,4
]}

机构：

[1] China Med Univ, Clin Trials & Translat Ctr, Shengjing Hosp, Shenyang, Peoples R China

[2] Liaoning Key Lab Precis Med Res Major Chron Dis, Shenyang, Peoples R China

[3] China Med Univ, Shengjing Hosp, Dept Pulm & Crit Care Med, Shenyang, Peoples R China

[4] China Med Univ, Shengjing Hosp, Dept Clin Epidemiol, Shenyang, Peoples R China

[5] Huazhong Univ Sci & Technol, Sch Publ Hlth, Dept Nutr & Food Hyg, Hubei Key Lab Food Nutr & Safety,Tongji Med Coll, Wuhan, Peoples R China

[6] China Med Univ, Shengjing Hosp, Dept Pediat, Shenyang, Peoples R China

来源：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 2024年 / 282卷

基金：

中国国家自然科学基金;

关键词：

Chronic respiratory disease; Mortality; Noise; Air pollution; COPD; Asthma; ROAD TRAFFIC NOISE; ENVIRONMENTAL NOISE; CARDIOVASCULAR-DISEASE; PATTERNS; TRENDS; MODEL; RISK;

D O I：

10.1016/j.ecoenv.2024.116740

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Background: Chronic respiratory diseases (CRDs) are among the top three causes of human mortality. The relationship between modifiable environmental risk factor of noise and risk of mortality in CRDs is unclear. We investigated the longitudinal association between environmental noise exposure and cause-specific mortality in individuals with CRDs, considering the modifying effect of air pollution. Methods: Residential noise exposure was modelled using Common Noise Assessment Methods in Europe. Information on death causes were acquired from death registry data. Cox proportional-hazards models were used to estimate effect sizes. Results: Among 41,222 participants selected from UK Biobank with CRDs in baseline, a total of 3618 death cases occurred during an average follow-up of 12 years with mortality density of 7.16 per 1000 person years. Exposure with highest noise level ( > percentile 90) were associated with 22 % (Hazard ratio [HR] = 1.22, 95 % confidence interval [CI]: 1.05, 1.42), 71 % (HR = 1.71, 95 % CI: 1.14, 2.56), and 84 % (HR = 1.84, 95 % CI: 1.10, 3.07) increased risks for all-cause, respiratory disease (RD)-cause, and COPD-cause mortalities, separately. Both multiplicative and additive interactions was found between air pollution and noise with the risk of RD-cause mortality. Participants with high air pollution and noise exposure were associated with a 101 % (HR = 2.01, 95 % CI: 1.10, 3.66) increased risk of RD-cause mortality. Conclusion: It is imperative to mitigate noise exposure as a preventive measure against incident mortality in individuals with CRDs.

引用

页数：8