Di-μ-(1-(3-(1H-imidazol-1-yl)propyl)-2-methyl-4-oxo-1,4-dihydropyridin-3-olate)-bis[(η5-pentamethylcyclopentadienyl)iridium(III)] Chloride

被引:0
作者
Shutkov, Ilya A. [1 ]
Melnichuk, Nikolai A. [1 ]
Lyssenko, Konstantin A. [1 ]
Borisova, Nataliya E. [1 ]
Kovaleva, Olga N. [2 ]
Nazarov, Alexey A. [1 ]
机构
[1] Moscow MV Lomonosov State Univ, Dept Chem, Leninskie Gory 1-3, Moscow 119991, Russia
[2] NI Pirogov Russian Natl Res Med Univ, Fac Gen Med, Ostrovitianov Str 1, Moscow 117997, Russia
基金
俄罗斯科学基金会;
关键词
metallacycles; iridium complex; pyrone; maltol; anticancer activity; IRIDIUM(III) COMPLEXES; ANTICANCER ACTIVITY; CRYSTAL;
D O I
10.3390/M1816
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A metallacyclic maltol-tethered organometallic Ir(III) half-sandwich complex was synthesized as an analog of the ruthenium anticancer complexes (RAPTA/RAED) to evaluate its in vitro antiproliferative activity against various human cancer cell lines.
引用
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页数:5
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