Depersonalization, Meditation, and the Experience of (No-)Self

This paper aims to contribute to an integrated understanding of what goes missing in adverse meditation experiences and in cases of depersonalization disorder. Depersonalization disorder is characterized by distressing alterations in, and sometimes the complete disappearance of, the 'I' -sense. This paper examines the nature of the 'I' -sense and what it means to lose it from a Buddhist perspective. We argue for a nihilist position that the loss of the sense of self arises from misidentifications of the psychophysical complex with non -self elements, such as memories, thoughts, or body movements. Drawing from meditation experiences and depersonalization symptoms, we propose that the sense of self is not a static entity given in experience but fluctuates between various senses of self (and no -self) depending on circumstances. This pluralistic understanding of the various senses of self offers a more nuanced understanding of symptoms in depersonalization disorder and adverse effects of meditation practices.