Five years of advances in electrochemical analysis of protein biomarkers in lung cancer: a systematic review

被引:0
作者
Regiart, Matias [1 ]
Fernandez-Baldo, Martin A. [1 ]
Navarrete, Bernardino Alcazar [2 ,3 ,4 ]
Garcia, Concepcion Morales [2 ,3 ]
Gomez, Beatriz [2 ,3 ]
Tortella, Gonzalo R. [5 ,6 ]
Valero, Teresa [2 ,7 ]
Ortega, Francisco Gabriel [2 ,3 ,8 ,9 ]
机构
[1] Univ Nacl San Luis, Dept Quim, Inst Quim San Luis INQUISAL, CONICET, San Luis, Argentina
[2] Inst Biomed Res, IBS Granada, Granada, Spain
[3] Hosp Univ Virgen Nieves, Pulmonol Unit, Granada, Spain
[4] Inst Salud Carlos III, CIBERES, Madrid, Spain
[5] Univ La Frontera, Fac Ingn & Ciencias, Ctr Excelencia Invest Biotecnol Aplicada Medio Amb, Temuco, Chile
[6] Univ La Frontera, Fac Ingn & Ciencias, Dept Ingn Quim, Temuco 4780000, Chile
[7] Univ Granada, Fac Pharm, Dept Med & Organ Chem, Excellence Res Unit Chem Appl Biomed & Environm, Granada 18071, Spain
[8] Univ Granada, Andalusian Reg Govt,Ctr Genom & Oncol Res, GENYO, Pfizer, Granada 18006, Spain
[9] UGC Cartuja, Dist Sanitario Granada Metropolitano, Granada, Spain
来源
FRONTIERS IN CHEMISTRY | 2024年 / 12卷
关键词
electrochemical methods; biosensors; lung cancer; diagnosis; biomarkers; clinical analysis; CYTOKERATIN; 19; FRAGMENT; TUMOR-MARKERS; CARCINOEMBRYONIC ANTIGEN; IMMUNOSENSOR; IMMUNOASSAY; GOLD; SOX2; CEA;
D O I
10.3389/fchem.2024.1390050
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Lung cancer is the leading cause of cancer death in both men and women. It represents a public health problem that must be addressed through the early detection of specific biomarkers and effective treatment. To address this critical issue, it is imperative to implement effective methodologies for specific biomarker detection of lung cancer in real clinical samples. Electrochemical methods, including microfluidic devices and biosensors, can obtain robust results that reduce time, cost, and assay complexity. This comprehensive review will explore specific studies, methodologies, and detection limits and contribute to the depth of the discussion, making it a valuable resource for researchers and clinicians interested in lung cancer diagnosis.
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页数:17
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