The centrosome: a critical hub for cell cycle regulation

被引：0
作者：
Yoshino, Yuki [1 ,2 ,3 ]
Fang, Zhenzhou [1 ,2 ]
Chiba, Natsuko [1 ,2 ,3 ]
机构：
[1] Tohoku Univ, Inst Aging Dev & Canc, Dept Canc Biol, 4-1 Seiryomachi,Aoba ku, Sendai 9808575, Japan
[2] Tohoku Univ, Grad Sch Life Sci, Lab Canc Biol, 4-1 Seiryomachi,Aoba ku, Sendai 9808575, Japan
[3] Tohoku Univ, Grad Sch Med, Dept Canc Biol, 4-1 Seiryomachi,Aoba ku, Sendai 9808575, Japan
来源：
TRENDS IN CELL BIOLOGY | 2024年 / 34卷 / 06期
关键词：
D O I：
10.1016/j.tcb.2024.04.003
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Cyclins and cyclin-dependent kinases (CDKs) localize to the centrosome, but their significance in the cell cycle is unclear. Recently, Roberts et al. revealed that centrosomal cyclin B-CDK is required for mitotic entry and phosphorylation of substrates. This suggests that the centrosome acts as a signaling hub controlling the cell cycle.
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收藏
页码：437 / 439
页数：3
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