Accuracy of Provider Predictions of Viral Suppression Among Adolescents and Young Adults With HIV in an HIV Clinical Program

被引:1
作者
Thrul, Johannes [1 ,2 ,3 ]
Yusuf, Hasiya [4 ]
Devkota, Janardan [1 ]
Owczarzak, Jill [5 ]
Ohene-Kyei, Elise Tirza [4 ]
Gebo, Kelly [6 ]
Agwu, Allison [4 ,6 ]
机构
[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mental Hlth, Baltimore, MD USA
[2] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA
[3] La Trobe Univ, Ctr Alcohol Policy Res, Melbourne, Australia
[4] Johns Hopkins Sch Med, Dept Pediat, 200 N Wolfe St, Room 3096, Baltimore, MD 21287 USA
[5] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Hlth Behav & Soc, Baltimore, MD USA
[6] Johns Hopkins Sch Med, Dept Med, Baltimore, MD USA
关键词
HIV; adolescents and young adults; provider; prediction; point of care testing; ADHERENCE; LOAD;
D O I
10.1177/23259582241252587
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background Providers caring for adolescents and young adults with HIV (AYA-HIV) mostly base their adherence counseling during clinical encounters on clinical judgment and expectations of patients' medication adherence. There is currently no data on provider predictions of viral suppression for AYA-HIV. We aimed to assess the accuracy of provider predictions of patients' viral suppression status compared to viral load results.Methods Providers caring for AYA-HIV were asked to predict the likelihood of viral suppression of patients before a clinical encounter and give reasons for their predictions. Provider predictions were compared to actual viral load measurements of patients. Patient data were abstracted from electronic health records. The final analysis included 9 providers, 28 patients, and 34 observations of paired provider predictions and viral load results.Results Provider prediction accuracy of viral suppression was low (59%, Cohen's Kappa = 0.16). Provider predictions of lack of viral suppression were based on nonadherence to medications, new patient status, or structural vulnerabilities (e.g., unstable housing). Anticipated viral suppression was based on medication adherence, history of viral suppression, and the presence of family or other social forms of support.Conclusions Providers have difficulty accurately predicting viral suppression among AYA-HIV and may base their counseling on incorrect assumptions. Rapid point-of-care viral load testing may provide opportunities to improve counseling provided during the clinical encounter. Accuracy of Provider Predictions of Viral Suppression among Adolescents and Young Adults with HIV in an HIV Clinical ProgramProviders caring for adolescents and young adults with HIV (AYA-HIV) mostly base their adherence counseling during clinical encounters on clinical judgment and expectations of patients' medication adherence. Currently, no data exist on provider predictions of viral suppression for AYA-HIV. We aimed to assess the accuracy of provider predictions of patients' viral suppression compared to viral load results. Providers caring for AYA-HIV were asked to predict the likelihood of viral suppression of patients before a clinical encounter with reasons for their predictions. Provider predictions were compared to actual viral load measurements of patients. Patient data were abstracted from electronic health records. The final analysis included nine providers, 28 patients, and 34 observations of paired provider predictions and viral load results. Provider prediction accuracy of viral suppression was low (59%, Cohen's Kappa=0.16). Provider predictions of lack of viral suppression were based on non-adherence to medications, new patient status, or structural vulnerabilities (e.g., unstable housing). Anticipated viral suppression was based on medication adherence, history of viral suppression, and presence of family or other social forms of support. Providers have difficulty predicting viral suppression among AYA-HIV and may base counseling on incorrect assumptions. Rapid point-of-care viral load testing may provide opportunities to improve counseling.
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页数:5
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共 25 条
[1]   Recruitment of Youth Living With HIV to Optimize Adherence and Virologic Suppression: Testing the Design of Technology-Based Community Health Nursing to Improve Antiretroviral Therapy (ART) Clinical Trials [J].
Agwu, Allison Lorna ;
Yusuf, Hasiya Eihuri ;
D'Angelo, Lawrence ;
Rathore, Mobeen ;
Marchesi, Jeanette ;
Rowell, Julia ;
Smith, Raina ;
Toppins, Jackie ;
Trexler, Constance ;
Carr, Rashida ;
Johnson, Betty ;
Selden, Aaron Keith ;
Mahmoudi, Saniyyah ;
Black, Susan ;
Guadamuz, Jisell ;
Huettner, Steven ;
Trent, Maria .
JMIR RESEARCH PROTOCOLS, 2020, 9 (12)
[2]  
[Anonymous], 2021, HIV in the United States and Dependent Areas
[3]  
[Anonymous], 2021, HIV Among Youth
[4]  
[Anonymous], 2019, Understanding the HIV Care Continuum, P4
[5]   Self-reported adherence and pharmacy refill adherence are both predictive for an undetectable viral load among HIV-infected migrants receiving cART [J].
Been, Sabrina K. ;
Yildiz, Elif ;
Nieuwkerk, Pythia T. ;
Pogany, Katalin ;
van de Vijver, David A. M. C. ;
Verbon, Annelies .
PLOS ONE, 2017, 12 (11)
[6]   Digital Gaming to Improve Adherence Among Adolescents and Young Adults Living With HIV: Mixed-Methods Study to Test Feasibility and Acceptability [J].
Castel, Amanda D. ;
Qasmieh, Saba ;
Greenberg, Daniel ;
Ellenberger, Nicole ;
Howell, Tyriesa Howard ;
Griffith, Caleb ;
Wilbourn, Brittany C. ;
Ganesan, Kavitha ;
Hussein, Nadia ;
Ralte, Gabriel ;
Rakhmanina, Natella .
JMIR SERIOUS GAMES, 2018, 6 (04)
[7]   Low-Level Viremia Is Associated With Cumulative Adherence to Antiretroviral Therapy in Persons With HIV [J].
Castillo-Mancilla, Jose R. ;
Morrow, Mary ;
Coyle, Ryan P. ;
Coleman, Stacey S. ;
Zheng, Jia-Hua ;
Ellison, Lucas ;
Bushman, Lane R. ;
Kiser, Jennifer J. ;
Anderson, Peter L. ;
MaWhinney, Samantha .
OPEN FORUM INFECTIOUS DISEASES, 2021, 8 (09)
[8]  
CDC, 2021, HIV Surveillance Report 2019, V32
[9]   The elusive gold standard - Future perspectives for HIV adherence assessment and intervention [J].
Chesney, Margaret A. .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2006, 43 :S149-S155
[10]   Improving Adherence to Antiretroviral Therapy for Youth Living with HIV/AIDS: A Pilot Study Using Personalized, Interactive, Daily Text Message Reminders [J].
Dowshen, Nadia ;
Kuhns, Lisa M. ;
Johnson, Amy ;
Holoyda, Brian James ;
Garofalo, Robert .
JOURNAL OF MEDICAL INTERNET RESEARCH, 2012, 14 (02)