Cu@Fe3O4/SiO2@MWCNTs promoted green synthesis of novel bis-1,4-dihydropyridines and evaluation of biological activity

This study examined the investigation of one-pot multicomponent reactions of actylacetone, 4-hydroxy-3-methoxybenzaldehyde, primary amines, and activated acetylenic compounds in an aqueous medium at room temperature in the presence of catalytic amounts of Cu@Fe3O4/SiO2@MWCNTs. The responses that were employed As a result, high-yielding bis-1,4-dihydropyridines and other novel compounds can be produced. Diphenyl-picrylhydrazine (DPPH) radical trapping is being used in this field of study to examine the antioxidant characteristics of some bis-1,4-dihydropyridines that are produced. Scholarly research now underway has concentrated on examining the antibacterial characteristics of chemical substances that have been produced. The bis-1,4-dihydropyridines was synthesized by an experimental procedure that demonstrated several notable features, such as rapid reaction kinetics, substantial product yields, and effortless separation of the catalyst from the reaction mixture.