An Unusual Presentation of Neurosarcoidosis in a 64-Year-Old Man: A Case Report

被引:0
作者
Gopal, Kalashree [1 ]
Howard, Jeremiah [1 ]
Ramaraj, Shyamalee [1 ,2 ]
Shroff, Ahaj H. [2 ]
Gamard, Christopher [3 ]
机构
[1] Alabama Coll Osteopath Med, Internal Med, Dothan, AL 36303 USA
[2] Alabama Coll Osteopath Med, Neurol, Dothan, AL USA
[3] Mobile Infirm Med Ctr, Internal Med, Mobile, AL USA
关键词
diplopia; hilar lymphadenopathy; uveitis; rare cause of dysphagia; antidiuretic hormone and neurosarcoidosis; atypical sarcoid;
D O I
10.7759/cureus.60146
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Sarcoidosis is a multisystem granulomatous disorder with an unknown etiology that typically involves the lungs, skin, and lymph nodes, with neurological involvement being relatively rare. We discuss a case of neurosarcoidosis in a 64-year-old man who initially presented with unexplained cognitive impairment, insomnia, hyponatremia, paresthesias, and weight loss and later developed uveitis, diplopia, and dysphagia. Ultimately, findings of hilar and mediastinal lymphadenopathy on chest computed tomography (CT) resulted in bronchoscopy, which led to the diagnosis. This case highlights a rare presentation of sarcoidosis with an unusual constellation of symptoms. We discuss the difficulty involved in diagnosing this disorder as well as its highly variable course.
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页数:5
相关论文
共 10 条
[1]   Sarcoidosis: a review for the internist [J].
Bargagli, Elena ;
Prasse, Antje .
INTERNAL AND EMERGENCY MEDICINE, 2018, 13 (03) :325-331
[2]   Neuro-ophthalmic sarcoidosis [J].
Baughman, Robert P. ;
Weiss, Kenneth L. ;
Golnik, Karl C. .
EYE AND BRAIN, 2012, 4 :13-25
[3]   Sleep disturbance and symptom burden in sarcoidosis [J].
Benn, Bryan S. ;
Lehman, Zoe ;
Kidd, Sharon A. ;
Miaskowski, Christine ;
Sunwoo, Bernie Y. ;
Ho, Melissa ;
Sun, Sara ;
Ramstein, Joris ;
Gelfand, Jeffrey M. ;
Koth, Laura L. .
RESPIRATORY MEDICINE, 2018, 144 :S35-S40
[4]   Hypothalamic-Pituitary Axis Dysfunction, Central Diabetes Insipidus, and Syndrome of Inappropriate Antidiuretic Hormone Secretion as the First Clinical Presentation of Neurosarcoidosis: Why Early Diagnosis and Treatment is Important? [J].
Blazin, Tatjana ;
Prajapati, Dhruvil ;
Mohammed, Linha M. ;
Dhavale, Meera ;
Abdelaal, Mohamed K. ;
Alam, A. B. M. Nasibul ;
Ballestas, Natalia P. ;
Mostafa, Jihan A. .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (11)
[5]   Neurosarcoidosis Pathophysiology, Diagnosis, and Treatment [J].
Bradshaw, Michael J. ;
Pawate, Siddharama ;
Koth, Laura L. ;
Cho, Tracey A. ;
Gelfand, Jeffrey M. .
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION, 2021, 8 (06)
[6]   Sarcoidosis: Causes, Diagnosis, Clinical Features, and Treatments [J].
Jain, Rashi ;
Yadav, Dhananjay ;
Puranik, Nidhi ;
Guleria, Randeep ;
Jin, Jun-O .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (04)
[7]   Sarcoidosis [J].
Llanos, Oscar ;
Hamzeh, Nabeel .
MEDICAL CLINICS OF NORTH AMERICA, 2019, 103 (03) :527-+
[8]   Dysphagia, an uncommon initial presentation of sarcoidosis [J].
Somal, Navjot ;
Karan, Ravi ;
Maharaj, Aarti ;
Halperin, Jeff ;
Boodhai, Brent ;
Lipton, Jeffrey ;
Masri, Daniel J. ;
Kumar, Kamlesh .
RESPIRATORY MEDICINE CASE REPORTS, 2022, 37
[9]  
Tavee Jinny O, 2014, Continuum (Minneap Minn), V20, P545, DOI 10.1212/01.CON.0000450965.30710.e9
[10]  
Voortman M, 2019, SARCOIDOSIS VASC DIF, V36, P2, DOI 10.36141/svdld.v36i1.7412