Osteolytic lesions as a presenting sign of acute myeloid leukemia: a case report

被引：0
作者：
Zhang, Jingqian [1 ,2 ]
Mu, Shidai [1 ]
Cai, Li [1 ]
Ai, Lisha [1 ]
Wu, Yaohui [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Union Hosp, Inst Hematol, Tongji Med Coll, Wuhan, Peoples R China
[2] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Key Lab Mol Biol Targeted Therapies,Minist Educ, Wuhan, Peoples R China
来源：
FRONTIERS IN ONCOLOGY | 2024年 / 14卷
基金：
中国国家自然科学基金;
关键词：
acute myeloid leukemia; osteolytic lesions; myeloid sarcoma; pancytopenia; diagnosis; case report; GRANULOCYTIC SARCOMA; CHLOROMA;
D O I：
10.3389/fonc.2024.1364266
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Osteolytic lesions are infrequently observed in adult patients with acute myeloid leukemia (AML). This report details the case of a 66-year-old male patient who presented with myeloid sarcoma (MS), osteolytic lesion and pancytopenia. Effective treatments were delayed due to diagnostic challenges and the rapid progression of the disease. It is essential to consider AML in the differential diagnosis when faced with a patient presenting osteolytic lesions and pancytopenia.
引用
收藏
页数：6
相关论文
共 23 条
[1]  
BenDayan D, 1996, ACTA HAEMATOL-BASEL, V96, P249
[2]   Extensive Bone Marrow Necrosis and Osteolytic Lesions in a Case of Acute Myeloid Leukemia Transformed from Polycythemia Vera [J].
Chambers, Isaac ;
Phu Truong ;
Kallail, K. James ;
Palko, William .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2016, 8 (06)
[3]  
DHARMASENA F, 1986, CANCER-AM CANCER SOC, V58, P2273, DOI 10.1002/1097-0142(19861115)58:10<2273::AID-CNCR2820581019>3.0.CO
[4]  
2-E
[5]   Singular case of osteolytic lesions revealing transformation of myeloproliferative syndrome to acute leukemia [J].
Duval, Guillaume ;
Meytadier, Helene ;
Bouvard, Beatrice .
JOINT BONE SPINE, 2019, 86 (02) :251-253
[6]   Osteolytic Bone Lesions - A Rare Presentation of AML M6 [J].
Geetha, N. ;
Sreelesh, K. P. ;
Priya, M. J. ;
Lali, V. S. ;
Rekha, N. .
MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, 2015, 7
[7]   Clinical features and outcomes of extramedullary myeloid sarcoma in the United States: analysis using a national data set [J].
Goyal, G. ;
Bartley, A. C. ;
Patnaik, M. M. ;
Litzow, M. R. ;
Al-Kali, A. ;
Go, R. S. .
BLOOD CANCER JOURNAL, 2017, 7 :e592-e592
[8]  
Kaushansky K, 2016, Williams hematology, V9th
[9]   Clinicopathological, Cytogenetic, and Prognostic Analysis of 131 Myeloid Sarcoma Patients [J].
Kawamoto, Keisuke ;
Miyoshi, Hiroaki ;
Yoshida, Noriaki ;
Takizawa, Jun ;
Sone, Hirohito ;
Ohshima, Koichi .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2016, 40 (11) :1473-1483
[10]   Value of positron emission tomography scan in staging cancers, and an unusual presentation of acute myeloid leukemia - Case 2. Detection of an appendiceal carcinoma by whole-body positron emission tomography after Caesarean section [J].
Krauss, K ;
Aydeniz, B ;
Dohmen, BM ;
Wehrmann, M ;
Wallwiener, D ;
Huober, J .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) :2966-2968
123