Glymphatic-stagnated edema induced by traumatic brain injury

被引：8

作者：

Eide, Per Kristian ^{[1
,2
]}

Ringstad, Geir ^{[3
,4
]}

机构：

[1] Oslo Univ Hosp, Rikshosp, Dept Neurosurg, Oslo, Norway

[2] Univ Oslo, Fac Med, Inst Clin Med, Oslo, Norway

[3] Oslo Univ Hosp, Rikshosp, Dept Radiol, Oslo, Norway

[4] Sorlandet Hosp, Dept Geriatr & Internal Med, Arendal, Norway

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 2024年 / 45卷 / 05期

关键词：

D O I：

10.1016/j.tips.2024.01.005

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Traumatic brain injury (TBI) outcomes are notably affected by brain edema. A recent report by Hussain et al. unveils a unique form, glymphatic-stagnated brain edema, that stems from impaired glymphatic and lymphatic drainage induced by noradrenergic activation. Consequently, pan-noradrenergic inhibition may emerge as an innovative treatment for TBI-related edema, challenging traditional therapeutic approaches.

引用

页码：388 / 390

页数：3

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