Silk-Based 3D Porous Scaffolds for Tissue Engineering

被引：6

作者：

Xiao, Menglin ^{[1
,2
]}

Yao, Jinrong ^{[1
,2
]}

Shao, Zhengzhong ^{[1
,2
]}

Chen, Xin ^{[1
,2
]}

机构：

[1] Fudan Univ, Shanghai Stomatol Hosp, Dept Macromol Sci, State Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China

[2] Fudan Univ, Sch Stomatol, Lab Adv Mat, Shanghai 200433, Peoples R China

来源：

ACS BIOMATERIALS SCIENCE & ENGINEERING | 2024年 / 10卷 / 05期

基金：

中国国家自然科学基金;

关键词：

silk fibroin; freeze-drying; n-butanoladdition; bone and cartilage; regeneration; 3-DIMENSIONAL FIBROIN/COLLAGEN SCAFFOLDS; FIBROIN SCAFFOLDS; IN-VITRO; COMPOSITE SCAFFOLDS; COLLAGEN SCAFFOLD; BIOCOMPATIBLE PROPERTIES; STEM-CELLS; FABRICATION; CARTILAGE; LIGAMENT;

D O I：

10.1021/acsbiomaterials.4c00373

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Silk fibroin, extracted from the silk of the Bombyx mori silkworm, stands out as a biomaterial due to its nontoxic nature, excellent biocompatibility, and adjustable biodegradability. Porous scaffolds, a type of biomaterial, are crucial for creating an optimal microenvironment that supports cell adhesion and proliferation, thereby playing an essential role in tissue remodeling and repair. Therefore, this review focuses on 3D porous silk fibroin-based scaffolds, first summarizing their preparation methods and then detailing their regenerative effects on bone, cartilage, tendon, vascular, neural, skin, hepatic, and tracheal epithelial tissue engineering in recent years.

引用

页码：2827 / 2840

页数：14

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