Advances in the study of tissue-engineered retinal pigment epithelial cell sheets

被引：0

作者：

Zhou, Wang ^{[1
,2
]}

Chai, Yujiao ^{[1
,2
]}

Lu, Shan ^{[2
,4
]}

Yang, Qiaohui ^{[1
,3
]}

Tang, Liying ^{[1
,2
]}

Zhou, Di ^{[1
,2
,3
,5
]}

机构：

[1] Cent South Univ, Sch Basic Med Sci, NHC Key Lab Human Stem & Reprod Engn, 8 Luyun Rd, Changsha 410205, Hunan, Peoples R China

[2] Natl Engn Res Ctr Human Stem Cells, Changsha, Peoples R China

[3] Reprod & Genet Hosp CITIC Xiangya, Changsha, Peoples R China

[4] Hunan Normal Univ, Hunan Guangxiu Hosp, Changsha, Peoples R China

[5] Natl Med Prod Adm, Natl Ctr Drug Evaluat, Beijing, Peoples R China

来源：

REGENERATIVE THERAPY | 2024年 / 27卷

基金：

中国国家自然科学基金;

关键词：

Retinal degenerative disease; Retinal pigment epithelial cells; Tissue engineering; MACULAR DEGENERATION; BRUCHS MEMBRANE; STEM-CELLS; AUTOLOGOUS TRANSPLANTATION; BACTERIAL CELLULOSE; SURGICAL APPROACH; CHOROID SHEET; RPE; SCAFFOLDS; SUPPORT;

D O I：

暂无

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Regarded as the most promising treatment modality for retinal degenerative diseases, retinal pigment epithelium cell replacement therapy holds significant potential. Common retinal degenerative diseases, including Age-related Macular Degeneration, are frequently characterized by damage to the unit comprising photoreceptors, retinal pigment epithelium, and Bruch's membrane. The selection of appropriate tissue engineering materials, in conjunction with retinal pigment epithelial cells, for graft preparation, can offer an effective treatment for retinal degenerative diseases. This article presents an overview of the research conducted on retinal pigment epithelial cell tissue engineering, outlining the challenges and future prospects. (c) 2024, The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/

引用

页码：419 / 433

页数：15

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