A Review of the Current Approach and Treatment Landscape for Stage III Non-Small Cell Lung Cancer

被引:4
作者
Sridhar, Arthi [1 ]
Khan, Hina [2 ]
Yohannan, Binoy [3 ]
Chan, Kok Hoe [2 ]
Kataria, Nilansh [4 ]
Jafri, Syed Hasan [2 ]
机构
[1] Mayo Clin, Dept Oncol, Rochester, MN 55901 USA
[2] Univ Texas Hlth Sci Ctr Houston, Dept Internal Med, Div Hematol & Oncol, Houston, TX 77030 USA
[3] Mayo Clin, Dept Hematol, Rochester, MN 55901 USA
[4] MedStar Washington Hosp Ctr, Dept Internal Med, Washington, DC 20010 USA
关键词
precision; oncology; personalized; PD-L1; immunotherapy; targeted; osimertinib; durvalumab; radiation; chemotherapy; POSITRON-EMISSION-TOMOGRAPHY; SOUTHWEST-ONCOLOGY-GROUP; PHASE-III; INDUCTION CHEMOTHERAPY; NEOADJUVANT ATEZOLIZUMAB; CONSOLIDATION DOCETAXEL; SURGICAL RESECTION; PLUS CHEMOTHERAPY; RISK-FACTORS; 8TH EDITION;
D O I
10.3390/jcm13092633
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The therapeutic landscape of the management of stage III non-small cell lung cancer (NSCLC) has drastically evolved with the incorporation of immunotherapy and targeted therapy. Stage III NSCLC accounts for one-third of the cases and the treatment strategy of these locally advanced presentations are diverse, ranging from surgical to non-surgical options; with the incorporation of chemo-immunotherapy, radiation, and targeted therapies wherever applicable. The staging of this disease has also changed, and it is essential to have a strong multidisciplinary approach to do justice to patient care. In this article, we aim to navigate the nuanced approaches in the diagnosis and treatment of stage III NSCLC and expand on the evolution of the management of this disease.
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页数:21
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