The Emerging Field of Cardioimmunology: Past, Present and Foreseeable Future

被引：5

作者：

Mann, Douglas L. ^{[1
]}

机构：

[1] Washington Univ, Ctr Cardiovasc Res, Sch Med, Cardiovasc Div, 660 S Euclid Ave,Box 8086, St Louis, MO 63110 USA

来源：

CIRCULATION RESEARCH | 2024年 / 134卷 / 12期

基金：

美国国家卫生研究院;

关键词：

atherosclerosis; heart failure; hypertension; myocarditis; pericarditis; TUMOR-NECROSIS-FACTOR; CHRONIC HEART-FAILURE; LEFT-VENTRICULAR PERFORMANCE; FACTOR-ALPHA GENE; DOUBLE-BLIND; BINDING-PROTEINS; CONTROLLED TRIAL; INNATE IMMUNITY; THERAPY; ETANERCEPT;

D O I：

10.1161/CIRCRESAHA.123.323656

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Over the past 30 years, the field of cardioimmunology has moved from being dismissed as a field that was chasing an epiphenomenon of little biological consequence to a scientific discipline that is providing important new insights into the immunologic basis for hypertension, atherosclerosis, myocarditis, pericarditis, autoimmune heart disease, and heart failure. In this article, we will review the conceptual insights and technical breakthroughs that have allowed the field to move forward, as well as the clinical trials in the cardioimmunology space, to provide a historical context for the articles that will appear in the compendium that is focused on the interface between cardioimmunology, myocardial function, and disease.

引用

页码：1663 / 1680

页数：18

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