SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL STUDIES OF CIPROFLOXACI-IMINES AND THEIR COMPLEXES WITH OXOZIRCONIUM(IV), DIOXOMOLYBDENUM(VI), AND DIOXOTUNGSTEN(VI)

被引：8

作者：

Al-Assafe, Amaal Y. ^{[1
]}

Al-Quaba, Rana A. S. ^{[2
]}

机构：

[1] Univ Mosul, Coll Educ Pure Sci, Chem Dept, Mosul, Iraq

[2] Univ Mosul, Dept Chem, Coll Sci, Mosul, Iraq

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA | 2024年 / 38卷 / 04期

关键词：

4-Nitro-1,2-phenylenediamine; Ciprofloxacin-imine; In-vitro antimicrobial activity; Zr complexes;

D O I：

10.4314/bcse.v38i4.11

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We synthesized and characterized ciprofloxacin-imine complexes, generated from ciprofloxacin and either 4-nitro-1,2-phenylenediamine (NO2PD) or 1,3-propanediamine (PD), in conjunction with zirconyl nitrate dihydrate, sodium molybdate dihydrate, and sodium tungstate dihydrate. Characterization involved numerous analytical methods, containing melting point determination, conductance dimensions, elemental analysis (CHN), metal content determination (%), infrared, electronic spectra, nuclear magnetic resonance, and mass spectrometry. Our findings reveal that the ligand as functions a tetra-dentate chelate binding to metal ions via azomethine and deprotonated carboxylate group. Additionally, the complexes and ligands were tested in contradiction of two types of bacteria (Staphylococcus aureus, Bacillus subtilis) and all prepared compounds showed good spectrum activity.

引用

页码：949 / 962

页数：14

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