The Role of Long Noncoding RNAs in Progression of Leukemia: Based on Chromosomal Location

被引：0

作者：

Sabaghi, Fatemeh ^{[1
]}

Sadat, Saina Yousefi ^{[2
]}

Mirsaeedi, Zohreh ^{[3
]}

Salahi, Aref ^{[1
]}

Vazifehshenas, Sara ^{[4
]}

Kesh, Neda Zahmat ^{[5
]}

Balavar, Mahdieh ^{[6
]}

Ghoraeian, Pegah ^{[4
]}

机构：

[1] Islamic Azad Univ, Fac Adv Sci & Technol, Dept Mol Cell Biol, Tehran Med Sci, Tehran, Iran

[2] Islamic Azad Univ, Fac Adv Sci & Technol, Dept Microbiol, Tehran Med Sci, Tehran, Iran

[3] Islamic Azad Univ, Fac Adv Sci & Technol, Dept Cellular & Mol Biol, Tehran Med Sci, Tehran, Iran

[4] Islamic Azad Univ, Fac Adv Sci & Technol, Dept Genet, Tehran Med Sci, Tehran, Iran

[5] Islamic Azad Univ, Dept Genet, Zanjan Branch, Zanjan, Iran

[6] Falavarjan Branch Islamic Azad Univ, Dept Genet, Falavarjan, Iran

来源：

MICRORNA | 2024年 / 13卷 / 01期

关键词：

Biomarker; cancer; diagnosis; drug resistance; LncRNA; metastasis; ACUTE MYELOID-LEUKEMIA; ACUTE LYMPHOBLASTIC-LEUKEMIA; REGULATES IMATINIB RESISTANCE; PROMOTES CELL-PROLIFERATION; TUMOR-SUPPRESSOR; POOR-PROGNOSIS; HEPATOCELLULAR-CARCINOMA; LUNG-CANCER; CODING RNA; EXPRESSION;

D O I：

10.2174/0122115366265540231201065341

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Long non-coding RNA [LncRNA] dysregulation has been seen in many human cancers, including several kinds of leukemia, which is still a fatal disease with a poor prognosis. LncRNAs have been demonstrated to function as tumor suppressors or oncogenes in leukemia. This study covers current research findings on the role of lncRNAs in the prognosis and diagnosis of leukemia. Based on recent results, several lncRNAs are emerging as biomarkers for the prognosis, diagnosis, and even treatment outcome prediction of leukemia and have been shown to play critical roles in controlling leukemia cell activities, such as proliferation, cell death, metastasis, and drug resistance. As a result, lncRNA profiles may have superior predictive and diagnostic potential in leukemia. Accordingly, this review concentrates on the significance of lncRNAs in leukemia progression based on their chromosomal position.

引用

页码：14 / 32

页数：19

共 175 条

[1] CircRNA-Associated CeRNAs Regulatory Axes in Retinoblastoma: A Systematic Scoping Review [J].

Asadi, Mohammad Reza ;

Moslehian, Marziyeh Sadat ;

Sabaie, Hani ;

Sharifi-Bonab, Mirmohsen ;

Hakimi, Parvin ;

Hussen, Bashdar Mahmud ;

Taheri, Mohammad ;

Rakhshan, Azadeh ;

Rezazadeh, Maryam .

FRONTIERS IN ONCOLOGY, 2022, 12

[2] Ultraconserved elements in the human genome [J].

Bejerano, G ;

Pheasant, M ;

Makunin, I ;

Stephen, S ;

Kent, WJ ;

Mattick, JS ;

Haussler, D .

SCIENCE, 2004, 304 (5675) :1321-1325

[3] Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance [J].

Bhat, Ajaz A. ;

Younes, Salma N. ;

Raza, Syed Shadab ;

Zarif, Lubna ;

Nisar, Sabah ;

Ahmed, Ikhlak ;

Mir, Rashid ;

Kumar, Sachin ;

Sharawat, Surender K. ;

Hashem, Sheema ;

Elfaki, Imadeldin ;

Kulinski, Michal ;

Kuttikrishnan, Shilpa ;

Prabhu, Kirti S. ;

Khan, Abdul Q. ;

Yadav, Santosh K. ;

El-Rifai, Wael ;

Zargar, Mohammad A. ;

Zayed, Hatem ;

Haris, Mohammad ;

Uddin, Shahab .

MOLECULAR CANCER, 2020, 19 (01)

[4] MiR-326 regulates the proliferation and apoptosis of endometrial cancer by targeting Bcl-2 [J].

Cai, Lily ;

Chen, Juan-Juan ;

Deng, Fu-Mou ;

Wang, Lei ;

Chen, Yu .

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2021, 47 (02) :621-630

[5] Microarray profiling of bone marrow long non-coding RNA expression in Chinese pediatric acute myeloid leukemia patients [J].

Cao, Lan ;

Xiao, Pei-Fang ;

Tao, Yan-Fang ;

Hu, Shao-Yan ;

Lu, Jun ;

Zhao, Wen-Li ;

Li, Zhi-Heng ;

Wang, Na-Na ;

Wang, Jian ;

Feng, Xing ;

Chai, Yi-Huan ;

Pan, Jian ;

Gu, Gui-Xiong .

ONCOLOGY REPORTS, 2016, 35 (02) :757-770

[6]

Chen BL, 2020, BRAZ J MED BIOL RES, V53, DOI [10.1590/1414-431X20209299, 10.1590/1414-431x20209299]

[7] Long non-coding RNAs in non-small cell lung cancer as biomarkers and therapeutic targets [J].

Chen, Jing ;

Wang, Rui ;

Zhang, Kai ;

Chen, Long-Bang .

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2014, 18 (12) :2425-2436

[8] YY1-Activated Long Noncoding RNA SNHG5 Promotes Glioblastoma Cell Proliferation Through p38/MAPK Signaling Pathway [J].

Chen, Lei ;

Gong, Xin ;

Huang, Mengyi .

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2019, 34 (09) :589-596

[9] Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia [J].

Chen, Lianxiang ;

Wang, Wei ;

Cao, Lixia ;

Li, Zhijun ;

Wang, Xing .

MOLECULES AND CELLS, 2016, 39 (04) :330-336

[10] LncRNA MAGI2-AS3 inhibits the self-renewal of leukaemic stem cells by promoting TET2-dependent DNA demethylation of the LRIG1 promoter in acute myeloid leukaemia [J].

Chen, Lijuan ;

Fan, Xu ;

Zhu, Jianhua ;

Chen, Xuexin ;

Liu, Yiling ;

Zhou, Hao .

RNA BIOLOGY, 2020, 17 (06) :784-793

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