Targeting ARID1A-mutated gastric cancer cells with synthetic lethal approaches

被引：0
|
作者：
Fang, Menghan
Lin, Youfen
Xue, Chaorong
Sheng, Kaiqin
Guo, Zegeng
Han, Yuting
Lin, Hanbin
Wu, Yuecheng
Howell, Stephen B.
Lin, Xu
Lin, Xinjian
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 06期
关键词：
D O I：
10.1158/1538-7445.AM2024-3221
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3221
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Therapeutic approaches for ARID1A-mutated ovarian cancer.
    Zhang, Rugang
    CLINICAL CANCER RESEARCH, 2020, 26 (13) : 26 - 26
  • [2] Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
    Benjamin G Bitler
    Katherine M Aird
    Azat Garipov
    Hua Li
    Michael Amatangelo
    Andrew V Kossenkov
    David C Schultz
    Qin Liu
    Ie-Ming Shih
    Jose R Conejo-Garcia
    David W Speicher
    Rugang Zhang
    Nature Medicine, 2015, 21 : 231 - 238
  • [3] Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
    Bitler, Benjamin G.
    Aird, Katherine M.
    Garipov, Azat
    Li, Hua
    Amatangelo, Michael
    Kossenkov, Andrew V.
    Schultz, David C.
    Liu, Qin
    Shih, Ie-Ming
    Conejo-Garcia, Jose R.
    Speicher, David W.
    Zhang, Rugang
    NATURE MEDICINE, 2015, 21 (03) : 231 - +
  • [4] CCNE1 Is a Novel Synthetic Lethal Target for ARID1A-Mutated Ovarian Clear Cell Carcinoma
    Kawahara, Naoki
    Yamada, Yuki
    Kawaguchi, Ryuji
    CANCER SCIENCE, 2023, 114 : 1845 - 1845
  • [5] Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated ovarian cancers.
    Bitler, Benjamin
    Shih, Le-Ming
    Zhang, Rugang
    CLINICAL CANCER RESEARCH, 2016, 22
  • [6] ARID1A-mutated cervical cancer depends on the activation of YAP signaling
    Gao, Fei
    Li, Peiling
    Kong, Xianchao
    Song, Tiefang
    Han, Qi
    Zhou, Suiyang
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2021, 26 (12): : 1411 - 1421
  • [7] Alterations of chromatin structure and TGF-β signaling in ARID1A-mutated colon cancer cells
    Kim, Jiwon
    Jang, Giyong
    Lee, Soo-Jin
    Lee, Sang Eun
    Cho, Sung-Yup
    CANCER RESEARCH, 2023, 83 (07)
  • [8] Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer
    Fukumoto, Takeshi
    Park, Pyoung Hwa
    Wu, Shuai
    Fatkhutdinov, Nail
    Karakashev, Sergey
    Nacarelli, Timothy
    Kossenkov, Andrew V.
    Speicher, David W.
    Jean, Stephanie
    Zhang, Lin
    Wang, Tian-Li
    Shih, Ie-Ming
    Conejo-Garcia, Jose R.
    Bitler, Benjamin G.
    Zhang, Rugang
    CELL REPORTS, 2018, 22 (13): : 3393 - 3400
  • [9] Synthetic lethal strategy of an EZH1/2 dual inhibitor, HM97662, for the treatment of ARID1A-mutated solid cancers
    Kim, Yu-Yon
    Jung, Seung Hyun
    Han, Seon Yeong
    Byun, Jooyun
    Lee, Gunwoo
    Lee, Miyoung
    Park, Junghwa
    Kong, Taeyeon
    Han, Hyesun
    Lee, Sang Hyun
    Ahn, Young Gil
    CANCER RESEARCH, 2024, 84 (06)
  • [10] A key HDAC6 dependency of ARID1A-mutated ovarian cancer
    Altucci, Lucia
    NATURE CELL BIOLOGY, 2017, 19 (08) : 889 - 890
12345