Successful treatment of infantile refractory bullous pemphigoid with baricitinib

被引:1
作者
Zhou, Weinan [1 ,2 ,3 ,4 ]
Tan, Yidong [1 ,2 ,3 ,4 ]
Chen, Xuanyi [1 ,2 ,3 ,4 ]
Zhang, Wenqing [1 ,2 ,3 ,4 ]
Sun, Zhe [1 ,2 ,3 ,4 ]
Shen, Yihang [1 ,2 ,3 ,4 ]
Yao, Zhirong [1 ,2 ,3 ,4 ]
Cheng, Ruhong [1 ,2 ,3 ,4 ]
Gu, Yan [1 ,2 ,3 ,4 ]
机构
[1] Shanghai Jiao Tong Univ, Xinhua Hosp, Dermatol Ctr, Sch Med, Shanghai, Peoples R China
[2] Shanghai Jiao Tong Univ, Xinhua Hosp, Dept Dermatol, Sch Med, 1665 Kongjiang Rd, Shanghai 200092, Peoples R China
[3] Shanghai Jiao Tong Univ, Inst Dermatol, Sch Med, Shanghai, Peoples R China
[4] Shanghai Jiao Tong Univ, Xinhua Hosp, Dermatol Ctr, Dept Allergy,Sch Med, Shanghai, Peoples R China
关键词
baricitinib; bullous pemphigoid; infant; Janus kinase inhibitors; therapeutics;
D O I
10.1111/ajd.14345
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Infantile bullous pemphigoid (BP) is a rare autoantibody-mediated skin disorder. We report the effective treatment of a 6-month-old infant with BP using baricitinib, a Janus kinase (JAK) inhibitor, after failure with steroids and intravenous immunoglobulin. The patient achieved full remission and discontinued all medications without any relapses. To our knowledge, this is the first case of baricitinib used in an infant with BP.
引用
收藏
页码:642 / 646
页数:5
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