Pertussis outbreak in neonates and young infants across Italy, January to May 2024: implications for vaccination strategies

被引：11

作者：

Poeta, Marco ^{[1
,2
]}

Moracas, Cristina ^{[2
,3
]}

Albano, Chiara ^{[4
]}

Petrarca, Laura ^{[5
]}

Maglione, Marco ^{[6
]}

Pierri, Luca ^{[7
]}

Carta, Maurizio ^{[8
]}

Montaldo, Paolo ^{[9
]}

Venturini, Elisabetta ^{[10
]}

De Luca, Maia ^{[11
]}

Buonsenso, Danilo ^{[12
]}

Brambilla, Ilaria ^{[13
]}

Giacomet, Vania ^{[14
]}

Lo Vecchio, Andrea ^{[1
,2
]}

Bruzzese, Eugenia ^{[1
,2
]}

Midulla, Fabio ^{[5
]}

Colomba, Claudia ^{[4
,15
]}

Guarino, Alfredo ^{[1
,2
]}

Outbreak, Pertussis ^{[1
]}

机构：

[1] Univ Naples Federico II, Dept Translat Med Sci, Naples, Italy

[2] Univ Hosp Federico II, Dept Maternal & Child Hlth, Pediat Infect Dis Unit, Naples, Italy

[3] Univ Pavia, Dept Publ Hlth Expt & Forens Med, PhD Natl Program One Hlth approaches Infect Dis &, Pavia, Italy

[4] Univ Palermo, Dept Hlth Promot Maternal & Infant Care Internal M, Palermo, Italy

[5] Sapienza Univ Rome, Dept Maternal Infantile & Urol Sci, Rome, Italy

[6] Stobono Pausilipon Childrens Hosp, Paediat Emergency Dept, Naples, Italy

[7] Santobono Pausilipon Childrens Hosp, Emergency Dept, Neonatal Intens Care Unit & Neonatol, Naples, Italy

[8] Univ Hosp Policlin Paolo Giaccone, Neonatol & Neonatal Intens Care Unit, Palermo, Italy

[9] Univ Campania Luigi Vanvitelli, Dept Woman Child Gen & Specialized Surg, Naples, Italy

[10] Meyer Childrens Hosp, Infect Dis Unit, Florence, Italy

[11] IRCCS, Bambino Gesu Childrens Hosp, Infect Dis Unit, Rome, Italy

[12] Fdn Policlin Univ A Gemelli IRCCS, Dept Woman & Child Hlth & Publ Hlth, Pediat Infect Dis & Clin Pediat Ultrasound, Rome, Italy

[13] Fdn IRCCS Policlin San Matteo, Dept Clin Surg Diagnost & Pediat Sci, Pavia, Italy

[14] Univ Milan, L Sacco Hosp, Dept Pediat, Pediat Infect Dis Unit, Milan, Italy

[15] G Di Cristina Hosp, Div Pediat Infect Dis, ARNAS Civ Cristina Benfratelli, Palermo, Italy

来源：

EUROSURVEILLANCE | 2024年 / 29卷 / 23期

关键词：

CHILDREN;

D O I：

10.2807/1560-7917.ES.2024.29.23.240030

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Since January 2024, Italy experiences a pertussis outbreak, primarily affecting neonates and unvaccinated infants at high risk of severe complications and mortality; 11 major paediatric centres noted 108 hospitalisations and three deaths by 10 May. The outbreak reflects increased circulation of Bordetella pertussis and nonadherence to immunisation recommendations during pregnancy. Public health interventions, including maternal immunisation, vaccination of infants as early as possible and post-exposure prophylaxis, are critical for reducing the burden of pertussis and preventing further mortality.

引用

页数：6

共 17 条

[1] Vaccination in Pregnancy against Pertussis: A Consensus Statement on Behalf of the Global Pertussis Initiative
Abu-Raya, Bahaa
Forsyth, Kevin
Halperin, Scott A.
Maertens, Kirsten
Jones, Christine E.
Heininger, Ulrich
Hozbor, Daniela
von Koenig, Carl Heinz Wirsing
Chitkara, Amar J.
Muloiwa, Rudzani
Tan, Tina Q.
[J]. VACCINES, 2022, 10 (12)
[2] Critical Pertussis Illness in Children: A Multicenter Prospective Cohort Study
Berger, John T.
Carcillo, Joseph A.
Shanley, Thomas P.
Wessel, David L.
Clark, Amy
Holubkov, Richard
Meert, Kathleen L.
Newth, Christopher J. L.
Berg, Robert A.
Heidemann, Sabrina
Harrison, Rick
Pollack, Murray
Dalton, Heidi
Harvill, Eric
Karanikas, Alexia
Liu, Teresa
Burr, Jeri S.
Doctor, Allan
Dean, J. Michael
Jenkins, Tammara L.
Nicholson, Carol E.
[J]. PEDIATRIC CRITICAL CARE MEDICINE, 2013, 14 (04) : 356 - 365
[3] Centers for Disease Control and Prevention (CDC), Whooping cough (pertussis)- postexposure antimicrobial prophylaxis
[4] Pertussis: New preventive strategies for an old disease
Di Mattia, Greta
Nicolai, Ambra
Frassanito, Antonella
Petrarca, Laura
Nenna, Raffaella
Midulla, Fabio
[J]. PAEDIATRIC RESPIRATORY REVIEWS, 2019, 29 : 68 - 73
[5] European Centre for Disease Prevention and Control (ECDC), 2024, Increase of pertussis cases in the EU/EEA
[6] Parents as source of pertussis transmission in hospitalized young infants
Fedele, Giorgio
Carollo, Maria
Palazzo, Raffaella
Stefanelli, Paola
Pandolfi, Elisabetta
Gesualdo, Francesco
Tozzi, Alberto Eugenio
Carsetti, Rita
Villani, Alberto
Nicolai, Ambra
Midulla, Fabio
Ausiello, Clara Maria
[J]. INFECTION, 2017, 45 (02) : 171 - 178
[7] Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections
Frassanito, A.
Nenna, R.
Nicolai, A.
Pierangeli, A.
Tozzi, A. E.
Stefanelli, P.
Carsetti, R.
Concato, C.
Schiavoni, I.
Midulla, F.
[J]. BMC INFECTIOUS DISEASES, 2017, 17
[8] Kimberlin DW., 2021, Red Book: 2021 Report of the Committee on Infectious Diseases, V32nd
[9] Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells
Marcellini, Valentina
Mortari, Eva Piano
Fedele, Giorgio
Gesualdo, Francesco
Pandolfi, Elisabetta
Midulla, Fabio
Leone, Pasqualina
Stefanelli, Paola
Tozzi, Alberto Eugenio
Carsetti, Rita
[J]. FRONTIERS IN IMMUNOLOGY, 2017, 8
[10] Predictors of Disease Severity in Children Hospitalized for Pertussis During an Epidemic
Marshall, Helen
Clarke, Michelle
Rasiah, Kavita
Richmond, Peter
Buttery, Jim
Reynolds, Graham
Andrews, Ross
Nissen, Michael
Wood, Nick
McIntyre, Peter
[J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2015, 34 (04) : 339 - 345

← 1 2 →