Polypharmacy and associated factors in South Korean elderly patients with dementia: An analysis using National Health Insurance claims data

被引:1
作者
Kim, Hea-Lim [1 ]
Lee, Hye-Jae [2 ]
机构
[1] Seoul Natl Univ, Grad Sch Publ Hlth, Dept Publ Hlth Sci, Seoul, South Korea
[2] Korea Natl Open Univ, Dept Environm Hlth, Seoul, South Korea
来源
PLOS ONE | 2024年 / 19卷 / 04期
基金
新加坡国家研究基金会;
关键词
PSYCHOLOGICAL SYMPTOMS; COMORBIDITY; MEDICATIONS; DISEASE; PEOPLE; TRENDS;
D O I
10.1371/journal.pone.0302300
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Dementia is accompanied by several symptoms, including cognitive function decline, as well as behavioral and psychological symptoms. Elderly patients with dementia often experience polypharmacy, the concurrent use of multiple medications, due to chronic comorbidities. However, research on polypharmacy in patients with dementia is limited. This study aimed to characterize polypharmacy and associated factors among elderly patients with dementia in South Korea, and compare the characteristics of patients with and without dementia patients.Methods From the National Health Insurance Service (NHIS)-Senior cohort database, we extracted data on patients aged >= 60 years who received outpatient treatment in 2019. Polypharmacy was defined as the concurrent use of five or more different oral medications for >= 90 days; excessive polypharmacy referred to the concurrent use of ten or more different oral medications for >= 90 days. We compared the prevalence of polypharmacy between patients with and without and identified the associated factors using a logistic regression model.Results About 70.3% and 23.7% of patients with dementia exhibited polypharmacy and excessive polypharmacy, respectively. After adjusting for conditions such as age and Charlson's comorbidity index, the likelihood of polypharmacy and excessive polypharmacy significantly increased over time after the diagnosis of dementia. Additionally, under the same conditions, Medical Aid beneficiaries with dementia were more likely to experience polypharmacy and excessive polypharmacy compared to patients with dementia covered by National Health Insurance (NHI).Conclusion This study reports the latest evidence on the status and risk factors of polypharmacy in elderly patients with dementia. We proposed that careful monitoring and management are required for patients at high risk for polypharmacy.
引用
收藏
页数:15
相关论文
共 50 条
  • [41] Clinical Outcomes, Health Care Costs and Prognostic Factors for Total Knee Arthroplasty: A Multilevel Analysis of a National Cohort Study Using Administrative Claims Data
    Buitrago, Giancarlo
    Ortiz, Jorge R.
    Camacho, Felipe
    JOURNAL OF KNEE SURGERY, 2022, 35 (04) : 384 - 392
  • [42] Economic outcomes associated with diagnosed behavioral symptoms among patients with dementia in the United States: a health care claims database analysis
    Khandker, Rezaul Karim
    Chekani, Farid
    Mirchandani, Kirti
    Kathe, Niranjan
    BMC GERIATRICS, 2023, 23 (01)
  • [43] Factors Associated with Lung Cancer Patients Refusing Treatment and Their Survival: A National Cohort Study under a Universal Health Insurance in Taiwan
    Huang, Hsiu-Ling
    Kung, Pei-Tseng
    Chiu, Chang-Fang
    Wang, Yueh-Hsin
    Tsai, Wen-Chen
    PLOS ONE, 2014, 9 (07):
  • [44] Dietary Assessment and Factors According to Fruits and Vegetables Intake in Korean Elderly People: Analysis of Data from the Korea National Health and Nutrition Examination Survey, 2013-2018
    Kwon, Yong-Suk
    Yang, Yu-Yeong
    Park, Younghee
    Park, Yoo-Kyoung
    Kim, Sohye
    NUTRIENTS, 2020, 12 (11) : 1 - 18
  • [45] Factors Associated with Ceftriaxone Nonsusceptibility of Streptococcus pneumoniae: Analysis of South African National Surveillance Data, 2003 to 2010
    von Mollendorf, Claire
    Cohen, Cheryl
    de Gouveia, Linda
    Quan, Vanessa
    Meiring, Susan
    Feldman, Charles
    Klugman, Keith P.
    von Gottberg, Anne
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58 (06) : 3293 - 3305
  • [46] Relationship between hospital specialization and health outcomes in patients with nonsurgical spinal joint disease in South Korea A nationwide evidence-based study using national health insurance data
    Jung, Boyoung
    Yeo, Jiyoon
    Kim, Sun Jung
    Ha, In-Hyuk
    MEDICINE, 2021, 100 (32) : E26832
  • [47] Factors associated with long-stay status in patients with schizophrenia: An analysis of national databases covering the entire Korean population
    Chung, Woojin
    Chang, Hoo-Sun
    Oh, Sun-Min
    Yoon, Chung-Won
    INTERNATIONAL JOURNAL OF SOCIAL PSYCHIATRY, 2013, 59 (03) : 207 - 216
  • [48] Characteristics and Epidemiology of Discharged Pneumonia Patients in South Korea Using the Korean National Hospital Discharge In-Depth Injury Survey Data from 2006 to 2017
    Lee, Kyunghee
    Hong, Kyunglan
    Kang, Sunghong
    Hwang, Jieun
    INFECTIOUS DISEASE REPORTS, 2021, 13 (03) : 730 - 741
  • [49] Prevalence and associated factors of facial palsy and lifestyle characteristics: data from the Korean National Health and Nutrition Examination Survey 2010-2012
    Chang, Young-Soo
    Choi, Ji Eun
    Kim, Seon Woo
    Baek, Sun-Young
    Cho, Yang-Sun
    BMJ OPEN, 2016, 6 (11):
  • [50] Fenofibrate Use Is Associated With Lower Mortality and Fewer Cardiovascular Events in Patients With Diabetes: Results of 10,114 Patients From the Korean National Health Insurance Service Cohort
    Jo, Sang-Ho
    Nam, Hyewon
    Lee, Jeongwoo
    Park, Sojeong
    Lee, Jungkuk
    Kyoung, Dae-Sung
    DIABETES CARE, 2021, 44 (08) : 1868 - 1876