Coronary artery calcification in Korean patients with incident dialysis

被引：3

作者：

Bae, Eunjin ^{[1
]}

Seong, Eun Yong ^{[2
]}

Han, Byoung-Geun ^{[3
]}

Kim, Dong Ki ^{[4
]}

Lim, Chun Soo ^{[5
]}

Kang, Shin-Wook ^{[6
]}

Park, Cheol Whee ^{[7
]}

Kim, Chan-Duck ^{[8
]}

Shin, Byung Chul ^{[9
]}

Kim, Sung Gyun ^{[10
]}

Chung, Wookyung ^{[11
]}

Park, Jae Yoon ^{[12
]}

Lee, Joo Yeon ^{[13
]}

Kim, Yon Su ^{[4
]}

机构：

[1] Gyeongsang Natl Univ, Dept Internal Med, Coll Med, Chang Won, South Korea

[2] Pusan Natl Univ, Dept Internal Med, Coll Med, Busan, South Korea

[3] Yonsei Univ, Dept Internal Med, Wonju Coll Med, Kangwon, South Korea

[4] Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea

[5] Seoul Natl Univ, Dept Internal Med, Boramae Med Ctr, Seoul, South Korea

[6] Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea

[7] Catholic Univ Korea, Dept Internal Med, Coll Med, Seoul, South Korea

[8] Kyungpook Natl Univ, Dept Internal Med, Sch Med, Daegu, South Korea

[9] Chosun Univ Hosp, Dept Internal Med, Gwangju, South Korea

[10] Hallym Univ, Dept Internal Med, Sacred Heart Hosp, Pyongchon, South Korea

[11] Gachon Univ, Gil Hosp, Dept Internal Med, Incheon, South Korea

[12] Dongguk Univ, Dept Internal Med, Med Ctr, Goyang, South Korea

[13] Sanofi Aventis Korea, Dept Med, Seoul, South Korea

来源：

HEMODIALYSIS INTERNATIONAL | 2017年 / 21卷 / 03期

关键词：

Cardiovascular disease; coronary artery calcification; end-stage renal disease; L-spine radiography; STAGE RENAL-DISEASE; VASCULAR CALCIFICATION; COMPUTED-TOMOGRAPHY; CARDIOVASCULAR RISK; CALCIUM; MANAGEMENT; MECHANISMS;

D O I：

10.1111/hdi.12493

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Patients with chronic kidney disease have an extremely high risk of developing cardiovascular disease (CVD). In patients with end-stage renal disease (ESRD), coronary artery calcification (CAC) is associated with increased mortality from CVD. Methods: The present study aimed to investigate the risk factors for CAC in Korean patients with incident dialysis. Data on 423 patients with ESRD who started dialysis therapy between December 2012 and March 2014 were obtained from 10 university-affiliated hospitals. CAC was identified by using noncontrast-enhanced cardiac multidetector computed tomography. The CAC score was calculated according to the Agatston score, with CAC-positive subjects defined by an Agatston score >0. Findings: Patients' mean age was 55.614.6 years, and 64.1% were men. The CAC-positive rate was 63.8% (270 of 423). Results of univariate analyses showed significant differences in age, sex, etiology of ESRD and comorbid conditions according to the CAC score. However, results of multiple regression analysis showed that only a higher age was significantly associated with the CAC score. Receiver operating characteristic curves showed that the sensitivity and specificity of L-spine radiography for diagnosing CAC were 56% and 91%, respectively, for diagnosing CAC (area under the curve, 0.735). Discussion: CAC was frequent in patients with incident dialysis, and multiple regression analysis showed that only age was significantly associated with the CAC score. In addition, L-spine radiography could be a helpful modality for diagnosing CAC in patients with incident dialysis.

引用

页码：367 / 374

页数：8

共 32 条

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