Three cases of sperm immobility for intracytoplasmic sperm injection using testicular sperm

被引：0

作者：

Mimura, Noboru ^{[1
]}

Takeshima, Teppei ^{[1
]}

Aoki, Shun ^{[1
]}

Saito, Tomoki ^{[1
]}

Karibe, Jurii ^{[1
]}

Yumura, Yasushi ^{[1
]}

机构：

[1] Yokohama City Univ, Med Ctr, Reprod Ctr, Dept Urol, Urafune Cho 4-57,Minami Ku, Yokohama, Kanagawa 2320024, Japan

来源：

IJU CASE REPORTS | 2024年 / 7卷 / 03期

关键词：

intracytoplasmic sperm injection; Kartagener's syndrome; multiple morphological abnormalities of the sperm flagella; primary ciliary dyskinesia; sperm immobility; PRIMARY CILIARY DYSKINESIA; SPERMATOZOA; MUTATIONS;

D O I：

10.1002/iju5.12702

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Sperm immobility is a condition in which sperm are viable but not motile. We reported three patients with sperm immobility, who underwent testicular sperm extraction-intracytoplasmic sperm injection. Case presentation: In case 1, a 32-year-old patient with sperm immobility had previously undergone intracytoplasmic sperm injection with ejaculated sperm; however, pregnancy was unsuccessful. testicular sperm extraction-intracytoplasmic sperm injection was performed at our clinic, and pregnancy was achieved. In case 2, a 23-year-old patient with clinical varicocele whose semen analysis revealed sperm immobility underwent varicocelectomy, without improvement. Using the hypo-osmotic swelling test technique, testicular sperm extraction-intracytoplasmic sperm injection was performed; however, pregnancy was not achieved. In case 3, a 44-year-old patient with sperm immobility underwent testicular sperm extraction, and motile sperm were retrieved. testicular sperm extraction-intracytoplasmic sperm injection using these sperm resulted in pregnancy. Conclusion: Although testicular sperm extraction-intracytoplasmic sperm injection is not considered a solution in patients with sperm immobility, pregnancies were achieved. testicular sperm extraction-intracytoplasmic sperm injection may be successful in some cases in which ejaculated sperm intracytoplasmic sperm injection is unsuitable.

引用

页码：210 / 212

页数：3

共 8 条

[1] Mutations in CCDC39 and CCDC40 are the Major Cause of Primary Ciliary Dyskinesia with Axonemal Disorganization and Absent Inner Dynein Arms [J].

Antony, Dinu ;

Becker-Heck, Anita ;

Zariwala, Maimoona A. ;

Schmidts, Miriam ;

Onoufriadis, Alexandros ;

Forouhan, Mitra ;

Wilson, Robert ;

Taylor-Cox, Theresa ;

Dewar, Ann ;

Jackson, Claire ;

Goggin, Patricia ;

Loges, Niki T. ;

Olbrich, Heike ;

Jaspers, Martine ;

Jorissen, Mark ;

Leigh, Margaret W. ;

Wolf, Whitney E. ;

Daniels, M. Leigh Anne ;

Noone, Peadar G. ;

Ferkol, Thomas W. ;

Sagel, Scott D. ;

Rosenfeld, Margaret ;

Rutman, Andrew ;

Dixit, Abhijit ;

O'Callaghan, Christopher ;

Lucas, Jane S. ;

Hogg, Claire ;

Scambler, Peter J. ;

Emes, Richard D. ;

Chung, Eddie M. K. ;

Shoemark, Amelia ;

Knowles, Michael R. ;

Omran, Heymut ;

Mitchison, Hannah M. .

HUMAN MUTATION, 2013, 34 (03) :462-472

[2] Primary ciliary dyskinesia: a consensus statement on diagnostic and treatment approaches in children [J].

Barbato, A. ;

Frischer, T. ;

Kuehni, C. E. ;

Snijders, D. ;

Azevedo, I. ;

Baktai, G. ;

Bartoloni, L. ;

Eber, E. ;

Escribano, A. ;

Haarman, E. ;

Hesselmar, B. ;

Hogg, C. ;

Jorissen, M. ;

Lucas, J. ;

Nielsen, K. G. ;

O'Callaghan, C. ;

Omran, H. ;

Pohunek, P. ;

Strippoli, M-P. F. ;

Bush, A. .

EUROPEAN RESPIRATORY JOURNAL, 2009, 34 (06) :1264-1276

[3]

Dhar D K, 2009, Mymensingh Med J, V18, P75

[4]

Kawasaki Akiko, 2015, Reproductive Medicine and Biology, V14, P195, DOI 10.1007/s12522-015-0210-z

[5] DNAI2 Mutations Cause Primary Ciliary Dyskinesia with Defects in the Outer Dynein Arm [J].

Loges, Niki Tomas ;

Olbrich, Heike ;

Fenske, Lale ;

Mussaffi, Huda ;

Horvath, Judit ;

Fliegauf, Manfred ;

Kuhl, Heiner ;

Baktai, Gyorgy ;

Peterffy, Erzsebet ;

Chodhari, Rahul ;

Chung, Eddie M. K. ;

Rutman, Andrew ;

O'Callaghan, Christopher ;

Blau, Hannah ;

Tiszlavicz, Laszlo ;

Voelkel, Katarzyna ;

Witt, Michal ;

Zietkiewicz, Ewa ;

Neesen, Juergen ;

Reinhardt, Richard ;

Mitchison, Hannah M. ;

Omran, Heymut .

AMERICAN JOURNAL OF HUMAN GENETICS, 2008, 83 (05) :547-558

[6] Assisted reproduction for infertile patients with 9+0 immotile spermatozoa associated with autosomal dominant polycystic kidney disease [J].

Okada, H ;

Fujioka, H ;

Tatsumi, N ;

Fujisawa, M ;

Gohji, K ;

Arakawa, S ;

Kato, H ;

Kobayashi, SI ;

Isojima, S ;

Kamidono, S .

HUMAN REPRODUCTION, 1999, 14 (01) :110-113

[7] Clinical detection, diagnosis and treatment of morphological abnormalities of sperm flagella: A review of literature [J].

Wang, Jiaxiong ;

Wang, Weizhuo ;

Shen, Liyan ;

Zheng, Aiyan ;

Meng, Qingxia ;

Li, Hong ;

Yang, Shenmin .

FRONTIERS IN GENETICS, 2022, 13

[8] Different fertilization rates between immotile testicular spermatozoa and immotile ejaculated spermatozoa for ICSI in men with Kartagener's syndrome: case reports [J].

Westlander, G ;

Barry, M ;

Petrucoo, O ;

Norman, RJ .

HUMAN REPRODUCTION, 2003, 18 (06) :1286-1288

← 1 →