Multi-Omics and Single-Cell Omics: New Tools in Drug Target Discovery

被引：0
作者：
Loscalzo, Joseph [1 ,2 ]
机构：
[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Room 630M, 77 Ave Louis Pasteur, Boston, MA 02115 USA
[2] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc Med, Boston, MA 02115 USA
来源：
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY | 2024年 / 44卷 / 04期
基金：
美国国家卫生研究院;
关键词：
gene expression profiling; genomics; prognosis; sequence analysis; DNA; signal-to-noise ratio; NETWORK MEDICINE;
D O I：
10.1161/ATVBAHA.124.320686
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：759 / 762
页数：4
相关论文
共 50 条
  • [21] cfOmics: a cell-free multi-Omics database for diseases
    Li, Mingyang
    Zhou, Tianxiu
    Han, Mingfei
    Wang, Hongke
    Bao, Pengfei
    Tao, Yuhuan
    Chen, Xiaoqing
    Wu, Guansheng
    Liu, Tianyou
    Wang, Xiaojuan
    Lu, Qian
    Zhu, Yunping
    Lu, Zhi John
    NUCLEIC ACIDS RESEARCH, 2024, 52 (D1) : D607 - D621
  • [22] Progress in multi-omics studies of osteoarthritis
    Wei, Yuanyuan
    Qian, He
    Zhang, Xiaoyu
    Wang, Jian
    Yan, Heguo
    Xiao, Niqin
    Zeng, Sanjin
    Chen, Bingbing
    Yang, Qianqian
    Lu, Hongting
    Xie, Jing
    Xie, Zhaohu
    Qin, Dongdong
    Li, Zhaofu
    BIOMARKER RESEARCH, 2025, 13 (01)
  • [23] Metagenomics and Single-Cell Omics Data Analysis for Human Microbiome Research
    Han, Maozhen
    Yang, Pengshuo
    Zhou, Hao
    Li, Hongjun
    Ning, Kang
    TRANSLATIONAL BIOMEDICAL INFORMATICS: A PRECISION MEDICINE PERSPECTIVE, 2016, 939 : 117 - 137
  • [24] Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy
    Liu, Pei-Pei
    Yu, Xin-Yue
    Pan, Qing-Qing
    Ren, Jia-Jun
    Han, Yu-Xuan
    Zhang, Kai
    Wang, Yan
    Huang, Yin
    Ban, Tao
    PHARMACEUTICALS, 2025, 18 (01)
  • [25] scLRTD : A Novel Low Rank Tensor Decomposition Method for Imputing Missing Values in Single-Cell Multi-Omics Sequencing Data
    Ni, Zhijie
    Zheng, Xiaoying
    Zheng, Xiao
    Zou, Xiufen
    IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2022, 19 (02) : 1144 - 1153
  • [26] A survey on data integration for multi-omics sample clustering
    Lovino, Marta
    Randazzo, Vincenzo
    Ciravegna, Gabriele
    Barbiero, Pietro
    Ficarra, Elisa
    Cirrincione, Giansalvo
    NEUROCOMPUTING, 2022, 488 : 494 - 508
  • [27] Predicting Drug Response Based on Multi-Omics Fusion and Graph Convolution
    Peng, Wei
    Chen, Tielin
    Dai, Wei
    IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 2022, 26 (03) : 1384 - 1393
  • [28] An overview of multi-omics technologies in rheumatoid arthritis: applications in biomarker and pathway discovery
    Gong, Xiangjin
    Su, Lanqian
    Huang, Jinbang
    Liu, Jie
    Wang, Qinglai
    Luo, Xiufang
    Yang, Guanhu
    Chi, Hao
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [29] Integration of Chemoinformatics and Multi-Omics Analysis Defines ECT2 as a Potential Target for Cancer Drug Therapy
    Soltan, Mohamed A.
    Eldeen, Muhammad Alaa
    Sajer, Bayan H.
    Abdelhameed, Reda F. A.
    Al-Salmi, Fawziah A.
    Fayad, Eman
    Jafri, Ibrahim
    Ahmed, Hebatallah Emam Mohammed
    Eid, Refaat A.
    Hassan, Hesham M.
    Al-Shraim, Mubarak
    Negm, Amr
    Noreldin, Ahmed E.
    Darwish, Khaled M.
    BIOLOGY-BASEL, 2023, 12 (04):
  • [30] A multi-omics analysis reveals CLSPN is associated with prognosis, immune microenvironment and drug resistance in cancers
    Chen, Yihong
    Wen, Haicheng
    Li, Yin
    Han, Ying
    Tan, Jun
    Guo, Cao
    Cai, Changjing
    Liu, Ping
    Peng, Yinghui
    Liu, Yihan
    Wang, Xinwen
    Zeng, Shan
    Feng, Ziyang
    Shen, Hong
    BIOLOGICAL PROCEDURES ONLINE, 2023, 25 (01)
12345