Nanoflowers Templated CuO/Cu Hybrid Metasurface for Sensitive THz-TDS Detection of Acetylcholine

被引:1
作者
Lee, Soo Hyun [1 ]
Kim, Taeyeon [1 ,2 ]
Seo, Minah [1 ,2 ]
机构
[1] Korea Inst Sci & Technol KIST, Sensor Syst Res Ctr, Seoul 02792, South Korea
[2] Korea Univ, KU KIST Grad Sch Converging Sci & Technol, Seoul 02841, South Korea
来源
ADVANCED SENSOR RESEARCH | 2024年 / 3卷 / 12期
基金
新加坡国家研究基金会;
关键词
CuO nanoflowers; hybrid metamaterials; hydrolysates; signal recovery; terahertz time-domain spectroscopy; TERAHERTZ SPECTROSCOPY; NANOSTRUCTURES; METAMATERIAL; HYDROLYSIS; ABSORPTION;
D O I
10.1002/adsr.202400041
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Achieving sensitive detection using terahertz (THz) time-domain spectroscopy (TDS) remains challenging due to the low probabilities of molecules being positioned within microscale active regions of typical THz metamaterials. The hybrid metamaterials are prepared with expanded active surface areas by templating CuO nanoflowers into Cu nanoslots through the one-step hydrothermal method. The optimum condition of CuO/Cu nanoslots is achieved with variations in optical transmittance and without alteration of resonance frequency (fres). The enhancement of detection efficiency is obtained with acetylcholine (ACh), which has a hydrolysis-transformable characteristic. The cleavage of ACh into two molecules, namely choline and acetic acid, poses a challenge for direct THz-TDS detection. This is because the altered molecular energy states do not match with the resonance frequencies of pristine Cu nanoslots. Since the CuO nanoflowers with high chemical reactivity became corroded by acetic acid, sufficient signal variations are observed. As a portion of CuO nanoflowers is decreased, the transmittance gradually reached the original state (i.e., recovery). For the ACh, the comparison of sensing performance (i.e., sensitivity, limit-of-detection, and correlation coefficient) between the CuO/Cu and Cu nanoslots is intensively performed. This research focuses on sensitively detecting acetylcholine in the terahertz range through the integration of CuO nanoflowers with Cu nanoslots. The terahertz transmittance measurements are recalibrated by incorporating acidic components hydrolyzed from acetylcholine. Through quantitative analysis, the hybrid metasurfaces with enhanced active sites exhibited sufficient variations in terahertz signals, revealing their potential for the sensitive detection of trace substances. image
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页数:7
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