Polymeric Microneedles for Health Care Monitoring: An Emerging Trend

被引:4
|
作者
Pereira, Raquel L. [1 ]
Vinayakumar, K. B. [1 ]
Sillankorva, Sanna [1 ]
机构
[1] INL Int Iberian Nanotechnol Lab, P-4715330 Braga, Portugal
来源
ACS SENSORS | 2024年 / 9卷 / 05期
关键词
microneedle; healthcare; monitoring; biomarkers; analyte; biosensor; interstitialfluid; bioreceptor; INTERSTITIAL FLUID; TRANSDERMAL DELIVERY; DRUG-DELIVERY; SAFETY; FABRICATION; ARRAY; PAIN; EXTRACTION; BIOMARKERS; BIOSENSORS;
D O I
10.1021/acssensors.4c00612
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Bioanalyte collection by blood draw is a painful process, prone to needle phobia and injuries. Microneedles can be engineered to penetrate the epidermal skin barrier and collect analytes from the interstitial fluid, arising as a safe, painless, and effective alternative to hypodermic needles. Although there are plenty of reviews on the various types of microneedles and their use as drug delivery systems, there is a lack of systematization on the application of polymeric microneedles for diagnosis. In this review, we focus on the current state of the art of this field, while providing information on safety, preclinical and clinical trials, and market distribution, to outline what we believe will be the future of health monitoring.
引用
收藏
页码:2294 / 2309
页数:16
相关论文
共 50 条
  • [1] Polymeric Microneedles: An Emerging Paradigm for Advanced Biomedical Applications
    Kulkarni, Deepak
    Gadade, Dipak
    Chapaitkar, Nutan
    Shelke, Santosh
    Pekamwar, Sanjay
    Aher, Rushikesh
    Ahire, Ankita
    Avhale, Manjusha
    Badgule, Rupali
    Bansode, Radhika
    Bobade, Bhujang
    SCIENTIA PHARMACEUTICA, 2023, 91 (02)
  • [2] Polymeric Microneedles Enhance Transdermal Delivery of Therapeutics
    Nguyen, Hiep X.
    Kipping, Thomas
    Banga, Ajay K.
    PHARMACEUTICS, 2024, 16 (07)
  • [3] Fabrication Methods of Microneedles with Polymeric Materials
    Choi, Hyewon
    Seo, Hyein
    Yoon, Hyunsik
    KOREAN JOURNAL OF CHEMICAL ENGINEERING, 2025, 42 (01) : 1 - 11
  • [4] Nanomaterial-Enhanced Microneedles: Emerging Therapies for Diabetes and Obesity
    Abbasi, Mehrnaz
    Boka, Divine Afunu
    Deloit, Hannah
    PHARMACEUTICS, 2024, 16 (10)
  • [5] Electrochemical Microneedles: Innovative Instruments in Health Care
    Liao, Zhijun
    Zhou, Qian
    Gao, Bingbing
    BIOSENSORS-BASEL, 2022, 12 (10):
  • [6] Microneedles as a Promising Technology for Disease Monitoring and Drug Delivery: A Review
    Shivaswamy, Rashmi Hulimane
    Binulal, Pranav
    Benoy, Aloysious
    Lakshmiramanan, Kaushik
    Bhaskar, Nitu
    Pandya, Hardik Jeetendra
    ACS MATERIALS AU, 2024, 5 (01): : 115 - 140
  • [7] Polymeric microneedles for transdermal protein delivery
    Ye, Yanqi
    Yu, Jicheng
    Wen, Di
    Kahkoska, Anna R.
    Gu, Zhen
    ADVANCED DRUG DELIVERY REVIEWS, 2018, 127 : 106 - 118
  • [8] Polymeric microneedles: design of a biomedical patch
    Coppola, Sara
    Del Giudice, Danila
    Ferraro, Vincenzo
    Vespini, Veronica
    Grilli, Simonetta
    Maffettone, Pier Luca
    PROCEEDINGS OF 2022 IEEE INTERNATIONAL WORKSHOP ON METROLOGY FOR INDUSTRY 4.0 & IOT (IEEE METROIND4.0&IOT), 2022, : 39 - 43
  • [9] The progress of fabrication designs of polymeric microneedles and related biomedical applications
    Jiang, Xue
    Zhang, Wen
    Terry, Richard
    Li, Wei
    BMEMAT, 2023, 1 (04):
  • [10] Nanomaterials-incorporated polymeric microneedles for wound healing applications
    Duan, Wei
    Xu, Keying
    Huang, Sheng
    Gao, Yue
    Guo, Yong
    Shen, Qiying
    Wei, Qiaolin
    Zheng, Wei
    Hu, Quan
    Shen, Jia-Wei
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2024, 659