Nanotechnology in tissue engineering: expanding possibilities with nanoparticles

被引:6
作者
Sardari, Sohrab [1 ]
Hheidari, Ali [2 ]
Ghodousi, Maryam [3 ]
Rahi, Amid [4 ]
Pishbin, Esmail [5 ]
机构
[1] Iran Univ Sci & Technol, Sch Mech Engn, Tehran 1311416846, Iran
[2] Islamic Azad Univ, Dept Mech Engn, Sci & Res Branch, Tehran, Iran
[3] Penn State Univ, Dept Mech Engn, University Pk, PA USA
[4] Kerman Univ Med Sci, Pathol & Stem Cell Res Ctr, Kerman, Iran
[5] Iranian Res Org Sci & Technol, Biomicrofluid Lab, Dept Elect Engn & Informat Technol, Tehran, Iran
关键词
tissue engineering; nanotechnology; regenerative medicine; organ engineering; MESENCHYMAL STEM-CELLS; AUTOLOGOUS CHONDROCYTE IMPLANTATION; ENHANCED MECHANICAL-PROPERTIES; BIOACTIVE GLASS NANOPARTICLES; DERMAL REGENERATION TEMPLATE; DIABETIC FOOT ULCERS; GOLD NANOPARTICLES; SILVER NANOPARTICLES; BACTERIAL CELLULOSE; IN-VITRO;
D O I
10.1088/1361-6528/ad5cfb
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Tissue engineering is a multidisciplinary field that merges engineering, material science, and medical biology in order to develop biological alternatives for repairing, replacing, maintaining, or boosting the functionality of tissues and organs. The ultimate goal of tissue engineering is to create biological alternatives for repairing, replacing, maintaining, or enhancing the functionality of tissues and organs. However, the current landscape of tissue engineering techniques presents several challenges, including a lack of suitable biomaterials, inadequate cell proliferation, limited methodologies for replicating desired physiological structures, and the unstable and insufficient production of growth factors, which are essential for facilitating cell communication and the appropriate cellular responses. Despite these challenges, there has been significant progress made in tissue engineering techniques in recent years. Nanoparticles hold a major role within the realm of nanotechnology due to their unique qualities that change with size. These particles, which provide potential solutions to the issues that are met in tissue engineering, have helped propel nanotechnology to its current state of prominence. Despite substantial breakthroughs in the utilization of nanoparticles over the past two decades, the full range of their potential in addressing the difficulties within tissue engineering remains largely untapped. This is due to the fact that these advancements have occurred in relatively isolated pockets. In the realm of tissue engineering, the purpose of this research is to conduct an in-depth investigation of the several ways in which various types of nanoparticles might be put to use. In addition to this, it sheds light on the challenges that need to be conquered in order to unlock the maximum potential of nanotechnology in this area.
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页数:28
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