MXene-Based Responsive Hydrogels and Applications in Wound Healing

In recent years, stimulation-responsive hydrogels have emerged as a promising vehicle for wound management and drug delivery. However, due to their limited therapeutic effect, there is an urgent need to develop new hydrogel systems that can achieve effective wound treatment. MXenes have been widely used in diagnostic, antimicrobial, and electrochemical sensing applications, and are increasingly being investigated for their potential in wound therapy. In this review, we present a comprehensive overview of responsive MXene-based hydrogels systems for wound repair, including their synthesis methods, structures, surface modification strategies, biomedical applications, cytotoxicity, and biocompatibility. We also discuss the opportunities and challenges that responsive MXene-based hydrogels are likely to face in the future. Overall, this review will be a useful resource for researchers and practitioners working on the development and application of responsive MXene-based hydrogels for wound treatment.