High Doses of Colchicine Act As "Silver Bullets" Against Severe COVID-19

被引：7
|
作者：
Lilov, Alexander [1 ]
Palaveev, Kiril [1 ]
Mitev, Vanyo [2 ]
机构：
[1] Sofia Dist Hosp, Specialized Hosp Act Treatment Pneumopneumonia Pht, Pulmonol, Sofia, Bulgaria
[2] Med Univ Sofia, Chem & Biochem, Sofia, Bulgaria
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 02期
关键词：
obesity; survival; colchicine; nlrp3; inflammasome; covid-19;
D O I：
10.7759/cureus.54441
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 48-year-old patient with a weight of 120 kg with type 2 diabetes mellitus, hypertension, and gout was hospitalized on the third day of the COVID-19 diagnosis. His general condition is relatively good, oxygen saturation is 89%. Despite starting standard treatment, on the seventh day from the onset of symptoms, the patient deteriorated sharply (oxygen saturation dropped to 74%). The negative development of the disease is interrupted with a loading dose of colchicine of 6 mg. This is a typical case of the life-saving effect of high but safe doses of colchicine in high-risk COVID-19 patients.
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页数：8
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