The problem of residual pain in the assessment of rheumatoid arthritis activity

被引:1
作者
Motyl, Gabriela [1 ,2 ]
Krupka, Wiktoria Maria [1 ,2 ]
Maslinska, Maria [3 ]
机构
[1] Med Univ Warsaw, 61 Zwirki & Wigury St, PL-02091 Warsaw, Poland
[2] Natl Inst Geriatr Rheumatol & Rehabil, Res Grp, Warsaw, Poland
[3] Natl Inst Geriatr Rheumatol & Rehabil, Early Arthrit Clin, Warsaw, Poland
来源
REUMATOLOGIA | 2024年 / 62卷 / 03期
关键词
rheumatoid arthritis; fibromyalgia; pain assessment; residual pain; CENTRAL SENSITIZATION; INTERNATIONAL PATIENT; FIBROMYALGIA; SCALE; DISEASE; RELIABILITY; SENSITIVITY; PAINDETECT; STRATEGIES; COMPONENTS;
D O I
10.5114/reum/189779
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Residual pain is a major unmet medical need observed in patients suffering from rheumatoid arthritis (RA), which decreases their quality of life, even after achieving remission or low disease activity. The article has two aims: 1) to present mechanisms involved in the pathophysiology of residual pain, both inflammatory and non-inflammatory, i.e. neuropathic and nociplastic pain, as well as secondary pain syndromes, i.e. osteoarthritis and fibromyalgia, which can contribute to residual pain; 2) to show the limitations of current disease activity measures recommended by European Alliance of Associations for Rheumatology (EULAR) and American College of Rheumatology (ACR), which raise the need for a separate assessment of pain, and examples of methods that could be used by medical professionals to assess the pain and make a differential diagnosis. In conclusion, establishing a valid method to assess pain is essential to identify the pathomechanism of residual pain and to create treatments tailored specifically to individual RA patients.
引用
收藏
页码:176 / 186
页数:11
相关论文
共 92 条
[1]   PAIN CHARACTERISTICS IN PEOPLE WITH ACTIVE RHEUMATOID ARTHRITIS RECEIVING ADALIMUMAB AND ABATACEPT: A FEASIBILITY TRIAL OF NOCICEPTIVE, NEUROPATHIC AND PAIN SENSITISATION COMPONENTS [J].
Ahmed, L. ;
Biddle, K. ;
Blundell, A. ;
Koushesh, S. ;
Kiely, P. ;
Sedgwick, P. ;
Sofat, N. .
ANNALS OF THE RHEUMATIC DISEASES, 2023, 82 :314-314
[2]   Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting [J].
Ahmed, Saqa ;
Magan, Tejal ;
Vargas, Mario ;
Harrison, Abiola ;
Sofat, Nidhi .
JOURNAL OF PAIN RESEARCH, 2014, 7 :579-588
[3]  
Anderson DL, 2001, ARTHRIT RHEUM-ARTHR, V45, P317, DOI 10.1002/1529-0131(200108)45:4<317::AID-ART343>3.0.CO
[4]  
2-X
[5]  
[Anonymous], Rheumatoid Arthritis: Diagnosis, Treatment, and Steps to Take
[6]   Rheumatoid Arthritis Severity Scale: a brief, physician-completed scale not confounded by patient self-report of psychological functioning [J].
Bardwell, WA ;
Nicassio, PM ;
Weisman, MH ;
Gevirtz, R ;
Bazzo, D .
RHEUMATOLOGY, 2002, 41 (01) :38-45
[7]   Identifying core domains to assess flare in rheumatoid arthritis: an OMERACT international patient and provider combined Delphi consensus [J].
Bartlett, Susan J. ;
Hewlett, Sarah ;
Bingham, Clifton O., III ;
Woodworth, Thasia G. ;
Alten, Rieke ;
Pohl, Christoph ;
Choy, Ernest H. ;
Sanderson, Tessa ;
Boonen, Annelies ;
Bykerk, Vivian ;
Leong, Amye L. ;
Strand, Vibeke ;
Furst, Daniel E. ;
Christensen, Robin .
ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (11) :1855-1860
[8]   Cellular and Molecular Mechanisms of Pain [J].
Basbaum, Allan I. ;
Bautista, Diana M. ;
Scherrer, Gregory ;
Julius, David .
CELL, 2009, 139 (02) :267-284
[9]   Risk profiling for a refractory course of rheumatoid arthritis [J].
Becede, Manuel ;
Alasti, Farideh ;
Gessl, Irina ;
Haupt, Lukas ;
Kerschbaumer, Andreas ;
Landesmann, Uriel ;
Loiskandl, Michaela ;
Supp, Gabriela M. ;
Smolen, Josef S. ;
Aletaha, Daniel .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 2019, 49 (02) :211-217
[10]  
Benjamin O., 2024, Disease-Modifying Antirheumatic Drugs (DMARD)