Imaging Genomics and Multiomics: A Guide for Beginners Starting Radiomics-Based Research

被引：3

作者：

Singh, Shiva ^{[1
]}

Mohajer, Bahram ^{[2
]}

Wells, Shane A. ^{[3
]}

Garg, Tushar ^{[2
]}

Hanneman, Kate ^{[4
]}

Takahashi, Takashi ^{[5
]}

Aldandan, Omran ^{[6
]}

McBee, Morgan P. ^{[7
]}

Jawahar, Anugayathri ^{[8
]}

机构：

[1] NIH, Radiol & Imaging Sci, Bethesda, MD USA

[2] Johns Hopkins Med, Radiol & Radiol Sci, Baltimore, MD USA

[3] Univ Michigan, Radiol, Ann Arbor, MI USA

[4] Univ Toronto, Med Imaging, Toronto, ON, Canada

[5] Univ Minnesota, Radiol, Minneapolis, MN USA

[6] Imam Abdulrahman Bin Faisal Univ, Coll Med Dammam, Dept Radiol, Eastern, Saudi Arabia

[7] Med Univ South Carolina, Radiol & Radiol Sci, Charleston, SC USA

[8] Northwestern Univ, Radiol, Feinberg Sch Med, 800 Arkes Pavil,676 N St Clair St, Chicago, IL 60611 USA

来源：

ACADEMIC RADIOLOGY | 2024年 / 31卷 / 06期

关键词：

Radiomics; Imaging; Genomics; Multiomics; Texture analysis; PERFORMANCE; BIOMARKERS; FRAMEWORK; PHENOTYPE; IMAGES;

D O I：

10.1016/j.acra.2024.01.024

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Radiomics uses advanced mathematical analysis of pixel-level information from radiologic images to extract existing information in traditional imaging algorithms. It is intended to find imaging biomarkers related to the genomics of tumors or disease patterns that improve medical care by advanced detection of tumor response patterns in tumors and to assess prognosis. Radiomics expands the paradigm of medical imaging to help with diagnosis, management of diseases and prognostication, leveraging image features by extracting information that can be used as imaging biomarkers to predict prognosis and response to treatment. Radiogenomics is an emerging area in radiomics that investigates the association between imaging characteristics and gene expression profiles. There are an increasing number of research publications using different radiomics approaches without a clear consensus on which method works best. We aim to describe the workflow of radiomics along with a guide of what to expect when starting a radiomics-based research project.

引用

页码：2281 / 2291

页数：11