To analyze the effect of Sipayi gingival solution and tinidazole tablets in the treatment of chronic periodontitis and to conduct a comparative study on their impact on periodontal index. Data of 84 individuals having chronic periodontitis admitted to Shaoxing Stomatological Hospital from January 2020 to January 2023 were selected and were randomly divided into two groups, observation and control group, each with 42 individuals (n=42). On the basis of basic treatment, the control group was treated with tinidazole, and the observation group was treated with Sipayi gingival solution. After treatment, clinical efficacy, periodontitis index levels, changes in inflammatory factors and drug safety were compared between the two groups. After taking the medication, efficacy of the medication in the observation group was higher than that in the control group (p<0.05). After treatment, periodontitis indicators in both groups were lower than before treatment, and the observation group was even lower (p<0.05). Levels of inflammatory factors in both groups were reduced after treatment, and the observation group was lower. Similarly, the incidence of adverse reactions in the observation group was lower than the control group (p<0.05). Sipay gingival fixing liquid medication regimen for chronic periodontitis can effectively control local periodontal infection, with good clinical efficacy and low incidence of adverse reactions and it is suitable for clinical promotion and application.
