Effectiveness and Safety of Antiobesity Medications in Patients With Obesity and Inflammatory Bowel Disease

被引：3
|
作者：
Pham, Jonathan T. [1 ]
Ghusn, Wissam [2 ,3 ]
Acosta, Andres [2 ,3 ]
Loftus, Edward V. [2 ]
Johnson, Amanda M. [2 ]
机构：
[1] Mayo Clin, Coll Med & Sci, Dept Internal Med, Rochester, MN USA
[2] Mayo Clin, Coll Med & Sci, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
[3] Mayo Clin, Coll Med & Sci, Precis Med Obes Program, Rochester, MN USA
来源：
AMERICAN JOURNAL OF GASTROENTEROLOGY | 2024年 / 119卷 / 06期
关键词：
inflammatory bowel disease; obesity; Crohn's disease; ulcerative colitis; antiobesity medications; CEREBROVASCULAR ACCIDENTS; RISK;
D O I：
10.14309/ajg.0000000000002490
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
INTRODUCTION: Limited data exist evaluating antiobesity medications (AOM) in patients with inflammatory bowel disease (IBD). METHODS: We performed a case-control study evaluating the effectiveness and safety of AOM in patients with IBD with obesity, matched to non-IBD controls. RESULTS: After 12 months, the case (n = 36) and control (n = 36) groups achieved similar percent total body weight loss of -6.9 +/- 8.3 and -8.1 +/- 7.0 (P = 0.30), respectively. Side effect profiles were similar between groups. Seven patients experienced an IBD flare, all managed medically. DISCUSSION: AOM use in patients with IBD demonstrated similar effectiveness and safety when compared with that observed in the non-IBD population.
引用
收藏
页码：1197 / 1200
页数：4
相关论文
共 50 条
  • [41] Examining the influence of inflammatory bowel disease medications on sleep quality
    Barnes, Alex
    Spizzo, Paul
    Bampton, Peter
    Andrews, Jane M.
    Fraser, Robert J.
    Mukherjee, Sutapa
    Mountifield, Reme
    JGH OPEN, 2023, 7 (03): : 190 - 196
  • [42] Therapeutic drug monitoring for biological medications in inflammatory bowel disease
    Cogan, Rachel
    El-Matary, Basem
    El-Matary, Wael
    SAUDI JOURNAL OF GASTROENTEROLOGY, 2022, 28 (05) : 322 - 331
  • [43] Adherence to treatment in patients with inflammatory bowel disease
    Andreev, K. A.
    Gorbenko, A., V
    Skirdenko, Yu. P.
    Nikolaev, N. A.
    Livzan, M. A.
    Bikbavova, G. R.
    Fedorin, M. M.
    BYULLETEN SIBIRSKOY MEDITSINY, 2021, 20 (03): : 120 - 128
  • [44] The Association of Medications and Vaccination with Risk of Pneumonia in Inflammatory Bowel Disease
    Gregory, Martin H.
    Ciorba, Matthew A.
    Wiitala, Wyndy L.
    Stidham, Ryan W.
    Higgins, Peter
    Morley, S. Celeste
    Hou, Jason K.
    Feagins, Linda A.
    Govani, Shail M.
    Cohen-Mekelburg, Shirley A.
    Waljee, Akbar K.
    INFLAMMATORY BOWEL DISEASES, 2020, 26 (06) : 919 - 925
  • [45] Relationship of visfatin with obesity and osteoporosis in patients with inflammatory bowel disease: a narrative review
    Ratajczak-Pawlowska, Alicja Ewa
    Szymczak-Tomczak, Aleksandra
    Hryhorowicz, Szymon
    Zawada, Agnieszka
    Skoracka, Kinga
    Rychter, Anna Maria
    Skrzypczak-Zielinska, Marzena
    Slomski, Ryszard
    Dobrowolska, Agnieszka
    Krela-Kazmierczak, Iwona
    FRONTIERS IN IMMUNOLOGY, 2025, 16
  • [46] Effectiveness and safety of probiotic preparations in clinical treatment of inflammatory bowel disease
    Wasilewska, Ewa
    Wroblewska, Barbara
    POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ, 2018, 72 : 159 - 174
  • [47] Safety and effectiveness of granulocyte and monocyte adsorptive apheresis in patients with inflammatory bowel disease in special situations: a multicentre cohort study
    Motoya, Satoshi
    Tanaka, Hiroki
    Shibuya, Tomoyoshi
    Osada, Taro
    Yamamoto, Takayuki
    Hongo, Hitoshi
    Mizuno, Chiemi
    Saito, Daisuke
    Aoyama, Nobuo
    Kobayashi, Toshihisa
    Ito, Hiroaki
    Tanida, Satoshi
    Nojima, Masanori
    Kokuma, Seiichiro
    Hosoi, Eiji
    BMC GASTROENTEROLOGY, 2019, 19 (01)
  • [48] Safety and effectiveness of granulocyte and monocyte adsorptive apheresis in patients with inflammatory bowel disease in special situations: a multicentre cohort study
    Satoshi Motoya
    Hiroki Tanaka
    Tomoyoshi Shibuya
    Taro Osada
    Takayuki Yamamoto
    Hitoshi Hongo
    Chiemi Mizuno
    Daisuke Saito
    Nobuo Aoyama
    Toshihisa Kobayashi
    Hiroaki Ito
    Satoshi Tanida
    Masanori Nojima
    Seiichiro Kokuma
    Eiji Hosoi
    BMC Gastroenterology, 19
  • [49] Systematic review with meta-analysis: real-world effectiveness and safety of vedolizumab in patients with inflammatory bowel disease
    Schreiber, Stefan
    Dignass, Axel
    Peyrin-Biroulet, Laurent
    Hather, Greg
    Demuth, Dirk
    Mosli, Mahmoud
    Curtis, Rebecca
    Khalid, Javaria Mona
    Loftus, Edward Vincent, Jr.
    JOURNAL OF GASTROENTEROLOGY, 2018, 53 (09) : 1048 - 1064
  • [50] Systematic review with meta-analysis: real-world effectiveness and safety of vedolizumab in patients with inflammatory bowel disease
    Stefan Schreiber
    Axel Dignass
    Laurent Peyrin-Biroulet
    Greg Hather
    Dirk Demuth
    Mahmoud Mosli
    Rebecca Curtis
    Javaria Mona Khalid
    Edward Vincent Loftus
    Journal of Gastroenterology, 2018, 53 : 1048 - 1064
12345