Effectiveness and Safety of Antiobesity Medications in Patients With Obesity and Inflammatory Bowel Disease

被引：3

作者：

Pham, Jonathan T. ^{[1
]}

Ghusn, Wissam ^{[2
,3
]}

Acosta, Andres ^{[2
,3
]}

Loftus, Edward V. ^{[2
]}

Johnson, Amanda M. ^{[2
]}

机构：

[1] Mayo Clin, Coll Med & Sci, Dept Internal Med, Rochester, MN USA

[2] Mayo Clin, Coll Med & Sci, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA

[3] Mayo Clin, Coll Med & Sci, Precis Med Obes Program, Rochester, MN USA

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 2024年 / 119卷 / 06期

关键词：

inflammatory bowel disease; obesity; Crohn's disease; ulcerative colitis; antiobesity medications; CEREBROVASCULAR ACCIDENTS; RISK;

D O I：

10.14309/ajg.0000000000002490

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

INTRODUCTION: Limited data exist evaluating antiobesity medications (AOM) in patients with inflammatory bowel disease (IBD). METHODS: We performed a case-control study evaluating the effectiveness and safety of AOM in patients with IBD with obesity, matched to non-IBD controls. RESULTS: After 12 months, the case (n = 36) and control (n = 36) groups achieved similar percent total body weight loss of -6.9 +/- 8.3 and -8.1 +/- 7.0 (P = 0.30), respectively. Side effect profiles were similar between groups. Seven patients experienced an IBD flare, all managed medically. DISCUSSION: AOM use in patients with IBD demonstrated similar effectiveness and safety when compared with that observed in the non-IBD population.

引用

页码：1197 / 1200

页数：4

共 50 条

[1] Effectiveness and Safety of Semaglutide for Weight Loss in Patients With Inflammatory Bowel Disease and Obesity
Desai, Aakash
Khataniar, Himsikhar
Hashash, Jana G.
Farraye, Francis A.
Regueiro, Miguel
Kochhar, Gursimran S.
INFLAMMATORY BOWEL DISEASES, 2024, : 696 - 705
[2] Safety and Effectiveness of Vedolizumab in Elderly Patients with Inflammatory Bowel Disease
Dahiya, Dushyant Singh
Chandan, Saurabh
Bapaye, Jay
Mohan, Babu P.
Ramai, Daryl
Kassab, Lena L.
Chandan, Ojasvini C.
Dulai, Parambir S.
Kochhar, Gursimran S.
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2024, 58 (04) : 378 - 388
[3] The Rising Epidemic of Obesity in Patients with Inflammatory Bowel Disease
Jellyana Peraza
Erin Abbott
Mark Shneyderman
Asher Kornbluth
Maitreyi Raman
Stephanie Gold
Current Treatment Options in Gastroenterology, 2024, 22 (3) : 134 - 144
[4] Impact of obesity on disease activity and disease outcome in inflammatory bowel disease: Results from the Swiss inflammatory bowel disease cohort
Greuter, Thomas
Porchet, Frederic
Braga-Neto, Manuel B.
Rossel, Jean-Benoit
Biedermann, Luc
Schreiner, Philipp
Scharl, Michael
Schoepfer, Alain M.
Safroneeva, Ekaterina
Straumann, Alex
Rogler, Gerhard
Vavricka, Stephan R.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 2020, 8 (10) : 1196 - 1207
[5] Impact of Obesity on Inflammatory Bowel Disease
Khakoo N.S.
Ioannou S.
Khakoo N.S.
Vedantam S.
Pearlman M.
Current Gastroenterology Reports, 2022, 24 (1) : 26 - 36
[6] The Impact of Obesity on Inflammatory Bowel Disease
Kaazan, Patricia
Seow, Warren
Yong, Shaanan
Heilbronn, Leonie K.
Segal, Jonathan P.
BIOMEDICINES, 2023, 11 (12)
[7] Interaction of obesity and inflammatory bowel disease
Harper, Jason W.
Zisman, Timothy L.
WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 22 (35) : 7868 - 7881
[8] Interaction of obesity and inflammatory bowel disease
Jason W Harper
Timothy L Zisman
World Journal of Gastroenterology, 2016, (35) : 7868 - 7881
[9] Safety and Efficacy of Bevacizumab in Cancer Patients with Inflammatory Bowel Disease
Herrera-Gomez, Ruth Gabriela
Grecea, Miruna
Gallois, Claire
Boige, Valerie
Pautier, Patricia
Pistilli, Barbara
Planchard, David
Malka, David
Ducreux, Michel
Mir, Olivier
CANCERS, 2022, 14 (12)
[10] Safety of Recombinant Zoster Vaccine in Patients with Inflammatory Bowel Disease
Satyam, Venkata R.
Li, Pei-Hsuan
Reich, Jason
Qazi, Taha
Noronha, Ansu
Wasan, Sharmeel K.
Farraye, Francis A.
DIGESTIVE DISEASES AND SCIENCES, 2020, 65 (10) : 2986 - 2991

← 1 2 3 4 5 →