Efficient Metal-Free Synthesis of Heterotriarylmethanes by 1,4-Addition of Benzofuran Azadienes

被引：0

作者：

Huang, Hong-Li ^{[1
]}

Li, Shan ^{[1
]}

Lv, Yong-Zheng ^{[1
]}

Shi, Ya-Qian ^{[1
]}

Liu, Chang-Bo ^{[2
]}

Peng, Zhongzhong ^{[3
]}

Gao, Fei ^{[4
]}

机构：

[1] Liaocheng Univ, Coll Chem & Chem Engn, Liaocheng 252059, Shandong, Peoples R China

[2] Liuyuan St Off Dongchangfu Dist, Liaocheng 252000, Shandong, Peoples R China

[3] Ningbo Hangzhou Bay Hosp, Ningbo 315336, Zhejiang, Peoples R China

[4] Shanghai Univ, Inst Translat Med, Shanghai 200444, Peoples R China

来源：

SYNLETT | 2024年

基金：

上海市自然科学基金;

关键词：

metal-free synthesis; heterocycles; benzofuran azadienes; heterotriarylmethanes; ENANTIOSELECTIVE SYNTHESIS; CONSTRUCTION; DERIVATIVES; INDOLES;

D O I：

10.1055/a-2370-6462

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient method has been established for synthesizing a variety of heterotriarylmethanes with good yields by employing a metal-free self-coupling reaction of benzofuran azadienes. The involvement of t-BuONa is essential in this process. Remarkably, this technique boasts mild reaction conditions and exceptional compatibility with various functional groups, rendering it a versatile and invaluable asset in the realm of organic synthesis.

引用

页码：484 / 487

页数：4

共 27 条

[21] Wang Y.-J., 2023, Chem. Eur. J, V29, pe202302111
[22] Pd-Catalyzed Enantioselective [6+4] Cycloaddition of Vinyl Oxetanes with Azadienes to Access Ten-Membered Heterocycles
Wang, Ya-Nong
Yang, Li-Cheng
Rong, Zi-Qiang
Liu, Tang-Lin
Liu, Ruoyang
Zhao, Yu
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (06) : 1596 - 1600
[23] Benzofuran derivatives and their anti-tubercular, anti-bacterial activities
Xu, Zhi
Zhao, Shijia
Lv, Zaosheng
Feng, Lianshun
Wang, Yinling
Zhang, Feng
Bai, Liuyang
Deng, Jialun
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 162 : 266 - 276
[24] One-pot synthesis of 2,3-disubstituted benzofurans from 2-chlorophenols using palladium-dihydroxyterphenylphosphine catalyst
Yamaguchi, Miyuki
Ozawa, Hayato
Katsumata, Haruka
Akiyama, Tomoyo
Manabe, Kei
[J]. TETRAHEDRON LETTERS, 2018, 59 (33) : 3175 - 3178
[25] Lewis Acid-Catalyzed [3+2]-Cyclization of Iodonium Ylides with Azadienes: Access to Spiro[benzofuran-2,2-furan]-3-ones
Yang, Liu
Pi, Chao
Wu, Yangjie
Cui, Xiuling
[J]. ORGANIC LETTERS, 2022, 24 (41) : 7502 - 7506
[26] Construction of pyrazole fused spiroketals by a (3+2) annulation reaction
Zhang, Wande
Wei, Xingfu
Wang, Yue
Huang, Yue
Nawaz, Shah
Qu, Jingping
Wang, Baomin
[J]. ORGANIC CHEMISTRY FRONTIERS, 2022, 9 (19) : 5197 - 5204
[27] Pd-catalyzed intramolecular Heck reaction for the synthesis of 2-methylbenzofurans
Zhou, Lixin
Shi, Yuxing
Zhu, Xueyan
Zhang, Peng
[J]. TETRAHEDRON LETTERS, 2019, 60 (30) : 2005 - 2008

← 1 2 3 →