Disseminated Cryptococcal Infection in Treatment-Naive Patients With Chronic Lymphocytic Leukemia (CLL)

被引：0

作者：

Gujabidze, Kakha ^{[1
]}

Hussain, Subaha Akram ^{[1
]}

Balint, Stephanie ^{[2
]}

Saadeh, Basel ^{[1
]}

Yucelen, Sumeyra ^{[1
]}

Shiferaw, Bethel ^{[3
]}

机构：

[1] St Marys Hosp, Internal Med, Waterbury, CT USA

[2] Quinnipiac Univ, Sch Med, Hamden, CT USA

[3] St Marys Hosp, Internal Med Infect Dis, Waterbury, CT 06706 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 04期

关键词：

cryptococcal neoformans; cll treatment; pulmonary cryptococcal infection; disseminated cryptococcus; chronic lymphocytic leukemia (cll); T-CELLS; MENINGITIS;

D O I：

10.7759/cureus.59022

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This case report highlights a rare occurrence of disseminated cryptococcal infection in an elderly male with untreated chronic lymphocytic leukemia (CLL). Despite lacking prior treatment for CLL, the patient presented with respiratory symptoms and was found to have Cryptococcus neoformans in blood cultures. Prompt initiation of antifungal therapy was crucial, although central nervous system involvement was absent. The case underscores the importance of considering fungal infections in CLL patients, emphasizing the immunological vulnerabilities associated with the disease. Heightened awareness and early management are essential in addressing such opportunistic infections in this patient population.

引用

页数：5

共 16 条

[1]

Allahmoradi E, 2017, IRAN J IMMUNOL, V14, P257, DOI IJIv14i4A1

[2] Virulence mechanisms and Cryptococcus neoformans pathogenesis [J].