Updates on Urinary Bladder Tumors With Neuroendocrine Features

被引:4
作者
Akbulut, Dilara [1 ]
Al-Ahmadie, Hikmat [2 ]
机构
[1] NCI, Lab Pathol, NIH, Bethesda, MD USA
[2] Mem Sloan Kettering Canc Ctr, Dept Pathol & Lab Med, New York, NY 10065 USA
关键词
Small cell carcinoma; large cell neuroendocrine carcinoma; well-differentiated neuroendocrine tumor; paraganglioma; ASCL1; NEUROD1; SMALL-CELL CARCINOMA; LONG-TERM OUTCOMES; UROTHELIAL CARCINOMA; RADICAL CYSTECTOMY; CHEMOTHERAPY; DIFFERENTIATION; CLASSIFICATION; PARAGANGLIOMA; THERAPY; NEUROD1;
D O I
10.1097/PAP.0000000000000433
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The most common neuroendocrine tumor in the urinary bladder is small cell carcinoma, which can be pure or mixed with components of urothelial or other histologic subtypes. Large cell neuroendocrine carcinoma of the bladder is rare and remains ill-defined but is increasingly recognized. Well-differentiated neuroendocrine tumor and paraganglioma can arise in the bladder but are very rare in this location. Recent advances in molecular characterization allowed for better classification and may offer improved stratification of these tumors.
引用
收藏
页码:169 / 177
页数:9
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