Phytochemistry and Pharmacological Activities of Panax japonicus: A Comprehensive Review

被引：0

作者：

Wang, Li ^{[1
,2
]}

Zhou, Ao-jia ^{[1
,2
]}

Zhang, Yi-dan ^{[2
]}

Fan, Cheng ^{[1
,2
]}

Hu, Shan-shan ^{[3
]}

Zhou, Zhi-yong ^{[3
]}

Yuan, Ding ^{[3
]}

Wang, Ting ^{[1
,2
]}

机构：

[1] Wuhan Univ Sci & Technol, Inst Pharmaceut Proc, Coll Med, Dept Pharm, Wuhan 430065, Hubei, Peoples R China

[2] Wuhan Univ Sci & Technol, Acad Nutr & Hlth, Dept Nutr Hyg & Toxicol, Hubei Prov Key Lab Occupat Hazard Identificat & Co, Wuhan, Hubei, Peoples R China

[3] Three Gorges Univ, Coll Med Sci, Dept Pharm, Yichang, Hubei, Peoples R China

来源：

PHARMACOGNOSY MAGAZINE | 2025年 / 21卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Panax japonicus (Family Araliaceae); phytochemistry; pharmacological activities; saponins; CHIKUSETSU SAPONIN IVA; DAMMARANE-TYPE SAPONINS; NF-KAPPA-B; ALPHA-GLUCOSIDASE INHIBITORS; ACTIVATED PROTEIN-KINASE; TRITERPENOID SAPONINS; OXIDATIVE STRESS; COGNITIVE IMPAIRMENT; CA MEYER; SPECIMENS;

D O I：

10.1177/09731296241259807

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Background: Panax japonicus (P. japonicus) belongs to the Panax genus of Araliaceae and is used as medicine mainly with the bamboo whiplike rhizome, which has the functions of dispelling blood stasis and hemostasis, attenuating swelling and pain, eradicating phlegm and relieving cough, tonifying, and strength. Purpose: This review intends to summarize the chemical constituents and pharmacological activities of P. japonicus to provide a scientific and systematic basis for better utilization of its rational applications. Methods: The literature was searched using PubMed, Baidu Scholar and Science Hub search engines. Results: The chemistry components isolated from P. japonicus are mainly saponins, besides also including polysaccharides, amino acids, volatile oils, inorganic elements, etc. P. japonicus exhibits extensive pharmacological activities including anti-inflammatory, antioxidant, lipid lowering activities, and therefore show extensive protective effects on the central nervous system, cardio-cerebrovascular system, digestive system. Conclusion: This article included a thorough summary of the botany, phytochemistry, and pharmacology of P. japonicus and provided evidence for its further research and clinical applications.

引用

页码：364 / 379

页数：16

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