Potential Anti-Tumorigenic Properties of Diverse Medicinal Plants against the Majority of Common Types of Cancer

被引:9
作者
Albahri, Ghosoon [1 ]
Badran, Adnan [2 ]
Abdel Baki, Zaher [3 ]
Alame, Mohamad [1 ]
Hijazi, Akram [1 ]
Daou, Anis [4 ]
Baydoun, Elias [5 ]
机构
[1] Plateforme Rech & Anal Sci Environm EDST PRASE, POB 657314, Beirut, Lebanon
[2] Univ Petra Amman Jordan, Dept Nutr, POB 961343, Amman, Jordan
[3] Amer Univ Middle East, Coll Engn & Technol, Egaila 54200, Kuwait
[4] Qatar Univ, Coll Pharm, Pharmaceut Sci Dept, QU Hlth, POB 2713, Doha, Qatar
[5] Amer Univ Beirut, Dept Biol, Beirut 1107, Lebanon
关键词
medicinal plants; availability; bioactive compounds; plant extraction; pharmacological activities; cancer treatment; INHIBITS CELL-PROLIFERATION; CURCUMIN INDUCES APOPTOSIS; HIBISCUS-SABDARIFFA L; NERIUM-OLEANDER; URTICA-DIOICA; IN-VITRO; ANTIOXIDANT ACTIVITY; PHENOLIC-COMPOUNDS; EXTRACT; CYCLE;
D O I
10.3390/ph17050574
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Globally, cancer is one of the primary causes of both morbidity and mortality. To prevent cancer from getting worse, more targeted and efficient treatment plans must be developed immediately. Recent research has demonstrated the benefits of natural products for several illnesses, and these products have played a significant role in the development of novel treatments whose bioactive components serve as both chemotherapeutic and chemo-preventive agents. Phytochemicals are naturally occurring molecules obtained from plants that have potential applications in both cancer therapy and the development of new medications. These phytochemicals function by regulating the molecular pathways connected to the onset and progression of cancer. Among the specific methods are immune system control, inducing cell cycle arrest and apoptosis, preventing proliferation, raising antioxidant status, and inactivating carcinogens. A thorough literature review was conducted using Google Scholar, PubMed, Scopus, Google Patent, Patent Scope, and US Patent to obtain the data. To provide an overview of the anticancer effects of several medicinal plants, including Annona muricata, Arctium lappa, Arum palaestinum, Cannabis sativa, Catharanthus roseus, Curcuma longa, Glycyrrhiza glabra, Hibiscus, Kalanchoe blossfeldiana, Moringa oleifera, Nerium oleander, Silybum marianum, Taraxacum officinale, Urtica dioica, Withania somnifera L., their availability, classification, active components, pharmacological activities, signaling mechanisms, and potential side effects against the most common cancer types were explored.
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页数:29
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