Amphiphilic cyclodextrin derivatives with antibacterial activity: chemical mutation and structure-activity relationship

被引:0
|
作者
Yamamura, Hatsuo [1 ]
Kato, Ayame [1 ]
Yamada, Eri [1 ]
Kato, Hisato [2 ]
Katsu, Takashi [2 ]
Masuda, Kazufumi [2 ]
Osawa, Kayo [3 ]
Miyagawa, Atsushi [1 ]
机构
[1] Nagoya Inst Technol, Grad Sch Engn, Gokiso Cho,Showa Ku, Nagoya 4668555, Japan
[2] Shujitsu Univ, Grad Sch Clin Pharm, 1-6-1 Nishigawara,Naka Ku, Okayama, Okayama 7038516, Japan
[3] Kobe Tokiwa Univ, Dept Med Technol, Div Hlth Sci, Kobe, 6530838, Japan
关键词
Cyclodextrins;
D O I
10.1039/d4nj01874e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The relationship between the membrane-disrupting antibacterial activities and the structures of cyclodextrin derivatives containing cationic and hydrophobic moieties was investigated. How cationic groups and hydrophobic groups are present on cyclodextrins determines their bacterial membrane disrupting antibacterial activity.
引用
收藏
页码:12355 / 12361
页数:7
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