Amphiphilic cyclodextrin derivatives with antibacterial activity: chemical mutation and structure-activity relationship

被引:0
|
作者
Yamamura, Hatsuo [1 ]
Kato, Ayame [1 ]
Yamada, Eri [1 ]
Kato, Hisato [2 ]
Katsu, Takashi [2 ]
Masuda, Kazufumi [2 ]
Osawa, Kayo [3 ]
Miyagawa, Atsushi [1 ]
机构
[1] Nagoya Inst Technol, Grad Sch Engn, Gokiso Cho,Showa Ku, Nagoya 4668555, Japan
[2] Shujitsu Univ, Grad Sch Clin Pharm, 1-6-1 Nishigawara,Naka Ku, Okayama, Okayama 7038516, Japan
[3] Kobe Tokiwa Univ, Dept Med Technol, Div Hlth Sci, Kobe, 6530838, Japan
关键词
Cyclodextrins;
D O I
10.1039/d4nj01874e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The relationship between the membrane-disrupting antibacterial activities and the structures of cyclodextrin derivatives containing cationic and hydrophobic moieties was investigated. How cationic groups and hydrophobic groups are present on cyclodextrins determines their bacterial membrane disrupting antibacterial activity.
引用
收藏
页码:12355 / 12361
页数:7
相关论文
共 50 条
  • [1] The antibacterial structure-activity relationship for common chitosan derivatives
    Rathinam, Sankar
    Solodova, Svetlana
    Kristjansdottir, Ingibjorg
    Hjalmarsdottir, Martha A.
    Masson, Mar
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 165 (165) : 1686 - 1693
  • [2] Antibacterial activities with the structure-activity relationship of coumarin derivatives
    Qin, Hua-Li
    Zhang, Zai-Wei
    Ravindar, Lekkala
    Rakesh, K. P.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 207
  • [3] Antibacterial activity of withanolides and their structure-activity relationship
    Lobatto, Virginia L.
    Garcia, Manuela E.
    Nicotra, Viviana E.
    Orozco, Clara I.
    Casero, Carina N.
    STEROIDS, 2023, 199
  • [4] Antibacterial Activity and Structure-Activity Relationship of a Series of Newly Synthesized Pleuromutilin Derivatives
    Li, Yun-Ge
    Wang, Ju-Xian
    Zhang, Guo-Ning
    Zhu, Mei
    You, Xue-Fu
    Hu, Xin-Xin
    Zhang, Fan
    Wang, Yu-Cheng
    CHEMISTRY & BIODIVERSITY, 2019, 16 (02)
  • [5] Synthesis and structure-activity relationship of rhodomyrtone derivatives as antibacterial agent
    Sukanlaya Leejae
    Boon-ek Yingyongnarongkul
    Apichart Suksamrarn
    Supayang Piyawan Voravuthikunchai
    Chinese Chemical Letters, 2012, 23 (09) : 1011 - 1014
  • [6] Synthesis and structure-activity relationship of rhodomyrtone derivatives as antibacterial agent
    Leejae, Sukanlaya
    Yingyongnarongkul, Boon-ek
    Suksamrarn, Apichart
    Voravuthikunchai, Supayang Piyawan
    CHINESE CHEMICAL LETTERS, 2012, 23 (09) : 1011 - 1014
  • [7] Structure-activity relationships of nitrofuran derivatives with antibacterial activity
    Pires, JR
    Giesbrecht, A
    Gomes, SL
    do-Amaral, AT
    MOLECULAR MODELING AND PREDICTION OF BIOACTIVITY, 2000, : 290 - 291
  • [8] Structure-activity relationship of antibacterial chalcones
    Avila, Hugo Pereira
    Albino Smania, Elza de Fatima
    Delle Monache, Franco
    Junior, Artur Smania
    BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (22) : 9790 - 9794
  • [9] Application of the dynamic quantitative structure-activity relationship method for modeling antibacterial activity of quinolone derivatives
    Kamenska, V
    Mekenyan, O
    Sterev, A
    Nedjalkova, Z
    ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1996, 46 (04): : 423 - 428
  • [10] Structure-Activity Relationship of Niclosamide Derivatives
    Tang, Zhonghai
    Acuna, Ulyana Munoz
    Fernandes, Nelson Freitas
    Chettiar, Somsundaram
    Li, Pui-Kai
    De Blanco, Esperanza Carcache
    ANTICANCER RESEARCH, 2017, 37 (06) : 2839 - 2843