Pleomorphic Carcinoma of the Breast: A Report of Three Cases

被引：0
作者：
Anass, El Achchi [1 ,2 ]
Amine, Majdoubi [1 ,2 ]
Mohamed, El Hammouti [1 ,2 ]
Bouhout, Tariq [1 ,2 ]
Serji, Badr [1 ,2 ]
机构：
[1] Mohammed VI Univ Hosp, Reg Oncol Ctr, Surg Oncol Dept, Oujda, Morocco
[2] Mohammed First Univ, Fac Med & Pharm, Oujda, Morocco
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 05期
关键词：
systemic chemotherapy; mastectomy; giant cell; pleomorphic carcinoma; breast carcinoma; INVASIVE LOBULAR CARCINOMA;
D O I：
10.7759/cureus.61091
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pleomorphic carcinoma (PC) is an uncommon and high-grade form of breast carcinoma characterized by the presence of distinctive pleomorphic giant tumor cells exhibiting bizarre nuclei and atypical mitosis. In this study, we report three patients who presented with lesions composed of a proliferation of large pleomorphic cells with a predominance of multinucleated giant cells on a microscope. Immunohistochemical analysis revealed distinct immunologic profiles within the respective malignant components. Notably, this report aims to contribute valuable insights, adding to the understanding of this uncommon tumor, accompanied by a literature review. Despite its rarity, PC in the breast remains clinically relevant due to its distinctive morphological and pathological features. These unique attributes require specific considerations in both clinical presentation and management.
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页数：6
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