Comorbid physical health outcomes in patients with bipolar disorder: An umbrella review of systematic reviews and meta-analyses

被引:4
作者
Kang, Jiseung [1 ,2 ]
Lee, Hyeri [3 ,4 ]
Park, Jaeyu [3 ,4 ]
Kim, Hyeon Jin [3 ,4 ]
Kwon, Rosie [3 ,4 ]
Kim, Sunyoung [5 ]
Fond, Guillaume [6 ]
Boyer, Laurent [6 ]
Rahmati, Masoud [6 ,7 ,8 ]
Smith, Lee [9 ]
Nehs, Christa J. [1 ,2 ]
Son, Yejun [3 ,10 ]
Kim, Soeun [3 ,10 ]
Lee, Hayeon [3 ,11 ]
Lee, Jinseok [11 ]
Kim, Min Seo [12 ,13 ]
Kim, Tae [14 ]
Yon, Dong Keon [3 ,4 ,15 ]
机构
[1] Harvard Med Sch, Div Sleep Med, Boston, MA USA
[2] Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA USA
[3] Kyung Hee Univ, Med Sci Res Inst, Ctr Digital Hlth, Coll Med, Seoul, South Korea
[4] Kyung Hee Univ, Dept Regulatory Sci, Seoul, South Korea
[5] Kyung Hee Univ, Med Ctr, Coll Med, Dept Family Med, Seoul, South Korea
[6] Aix Marseille Univ, Res Ctr Hlth Serv & Qual Life, AP HP, Marseille, France
[7] Lorestan Univ, Fac Literature & Human Sci, Dept Phys Educ & Sport Sci, Khorramabad, Iran
[8] Vali Easr Univ Rafsanjan, Fac Literature & Humanities, Dept Phys Educ & Sport Sci, Rafsanjan, Iran
[9] Anglia Ruskin Univ, Ctr Hlth Performance & Wellbeing, Cambridge, England
[10] Kyung Hee Univ, Coll Med, Dept Precis Med, Seoul, South Korea
[11] Kyung Hee Univ, Dept Biomed Engn, Yongin, South Korea
[12] Broad Inst MIT & Harvard, Cardiovasc Dis Initiat, 415 Main St, Cambridge, MA 02142 USA
[13] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA USA
[14] Gwangju Inst Sci & Technol, Dept Biomed Sci & Engn, 123 Cheomdangwagi ro, Gwangju 61005, South Korea
[15] Kyung Hee Univ, Dept Pediat, Coll Med, 23 Kyungheedae ro, Seoul 02447, South Korea
基金
新加坡国家研究基金会;
关键词
Bipolar disorder; Comorbid health outcomes; Umbrella review; CARDIOVASCULAR OUTCOMES; RISK; ASSOCIATION; PREVALENCE; LITHIUM; BIOMARKERS; PREDICTORS; MORTALITY; DEMENTIA; HISTORY;
D O I
10.1016/j.ajp.2024.104138
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Although several meta-analyses have examined the association between bipolar disorder (BD) and its comorbid health outcomes, this evidence has not been comprehensively assembled. Objective: We aimed to systematically review existing meta-analyses based on multiple physical outcomes and validate the evidence level by examining the existing certainty of evidence. Methods: We systematically searched databases, including PubMed/MEDLINE, Embase, Google Scholar, and CINAHL, for articles published up to July 2023. We included meta-analyses of cohort, case-control, and/or crosssectional studies investigating any comorbid health outcomes in patients with BD. We conducted quality assessments of the included meta-analysis using AMSTAR2. The credibility of findings was categorized into five levels of class and quality of evidence (CE), including convincing, highly suggestive, suggestive, weak, or not significant. Results: We analyzed 12 meta-analyses, including 145 original articles, covering 14 unique health outcomes with over 60 million participants across 29 countries and five continents. Among 14 health outcomes, BD was significantly associated with eight comorbid health outcomes, including dementia (equivalent odds ratio [eOR], 2.96 [95 % confidence intervals {CI}, 1.69 -5.17]; CE =suggestive), Parkinson 's disease (3.35 [1.72 -6.53]; CE =suggestive), asthma (1.86 [1.42 -2.42]; CE =weak), toxoplasmosis (1.69 [1.21 -2.37]; CE =weak), hypertension (1.28 [1.02 -1.60]; CE =convincing), breast cancer (1.33 [1.15 -1.55]; CE =weak), obesity (1.64 [1.30 -1.99]; CE =suggestive), and type 2 diabetes mellitus (1.98 [1.55 -2.52]; CE =weak). Conclusion: Individuals with BD are predisposed to numerous comorbid physical conditions, though these links are supported by various evidence levels and necessitate further studies. It is imperative that physicians be aware of these potential comorbidities in patients with BD and take proactive measures to manage them.
引用
收藏
页数:9
相关论文
共 50 条
  • [31] Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials
    Sun, Ming-Li
    Yao, Wei
    Wang, Xiao-Ying
    Gao, Song
    Varady, Krista A.
    Forslund, Sofia K.
    Zhang, Miao
    Shi, Zan-Yu
    Cao, Fan
    Zou, Bing-Jie
    Sun, Ming-Hui
    Liu, Ke-Xin
    Bao, Qi
    Xu, Jin
    Qin, Xue
    Xiao, Qian
    Wu, Lang
    Zhao, Yu-Hong
    Zhang, De-Yu
    Wu, Qi-Jun
    Gong, Ting-Ting
    ECLINICALMEDICINE, 2024, 70
  • [32] Vitamin E and Multiple Health Outcomes: An Umbrella Review of Meta-Analyses
    Xiong, Zheyu
    Liu, Linhu
    Jian, Zhongyu
    Ma, Yucheng
    Li, Hong
    Jin, Xi
    Liao, Banghua
    Wang, Kunjie
    NUTRIENTS, 2023, 15 (15)
  • [33] Health outcomes associated with phytosterols: An umbrella review of systematic reviews and meta-analyses of randomized controlled trials
    Liu, Bing
    Chen, Ke
    Chen, Xi
    Wang, Jian
    Shu, Guangjie
    Ping, Zhiguang
    Zhang, Shenshen
    PHYTOMEDICINE, 2024, 122
  • [34] Vitamin D3 and COVID-19 Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses
    Petrelli, Fausto
    Oldani, Simone
    Borgonovo, Karen
    Cabiddu, Mary
    Dognini, Giuseppina
    Ghilardi, Mara
    Parati, Maria Chiara
    Petro, Daniela
    Dottorini, Lorenzo
    Rea, Carmen
    Lonati, Veronica
    Luciani, Andrea
    Ghidini, Antonio
    ANTIOXIDANTS, 2023, 12 (02)
  • [35] The association between air pollution and obesity: an umbrella review of meta-analyses and systematic reviews
    Luo, Chengwen
    Wei, Ting
    Jiang, Weicong
    Yang, Yu-pei
    Zhang, Mei-Xian
    Xiong, Cai-Lian
    Tung, Tao-Hsin
    BMC PUBLIC HEALTH, 2024, 24 (01)
  • [36] Comorbid health conditions in people with attention-deficit/hyperactivity disorders: An umbrella review of systematic reviews and meta-analyses
    Kang, Jiseung
    Lee, Hyeri
    Kim, Soeun
    Kim, Hyeon Jin
    Lee, Hayeon
    Kwon, Rosie
    Son, Yejun
    Kim, Sunyoung
    Woo, Ho Geol
    Kim, Min Seo
    Koyanagi, Ai
    Smith, Lee
    Fond, Guillaume
    Boyer, Laurent
    Rahmati, Masoud
    Sanchez, Guillermo F. Lopez
    Dragioti, Elena
    Solmi, Marco
    Shin, Jae Il
    Kim, Tae
    Yon, Dong Keon
    Cortese, Samuele
    ASIAN JOURNAL OF PSYCHIATRY, 2024, 99
  • [37] Per- and polyfluoroalkyl substances and human health outcomes: An umbrella review of systematic reviews with meta-analyses of observational studies
    Xing, Wei-Yi
    Sun, Jia-Nan
    Liu, Fang-Hua
    Shan, Li-Shen
    Yin, Jia-Li
    Li, Yi-Zi
    Xu, He-Li
    Wei, Yi-Fan
    Liu, Jia-Xin
    Zheng, Wen-Rui
    Zhang, Ying-Ying
    Song, Xin-Jian
    Liu, Ke-Xin
    Liu, Jia-Cheng
    Wang, Jia-Yi
    Jia, Ming-Qian
    Chen, Xing
    Li, Xiao-Ying
    Liu, Chuan
    Gong, Ting-Ting
    Wu, Qi-Jun
    JOURNAL OF HAZARDOUS MATERIALS, 2024, 472
  • [38] Impact of Sedentary Behaviors on Blood Pressure and Cardiovascular Disease: An Umbrella Review of Systematic Reviews and Meta-Analyses
    O'Brien, Myles W.
    Shivgulam, Madeline E.
    Dominguez, Angelica Huerta
    Liu, Haoxuan
    Waghorn, Jocelyn
    Courish, Molly
    Tovar-Diaz, Jorge
    SPORTS MEDICINE, 2024, 54 (12) : 3097 - 3110
  • [39] Knee osteoarthritis and adverse health outcomes: an umbrella review of meta-analyses of observational studies
    Veronese, Nicola
    Honvo, Germain
    Bruyere, Olivier
    Rizzoli, Rene
    Barbagallo, Mario
    Maggi, Stefania
    Smith, Lee
    Sabico, Shaun
    Al-Daghri, Nasser
    Cooper, Cyrus
    Pegreffi, Francesco
    Reginster, Jean-Yves
    AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2023, 35 (02) : 245 - 252
  • [40] Effects of cognitive stimulation therapy on patients with dementia: An umbrella review of systematic reviews and meta-analyses
    Cao, Yanan
    Wang, Nana
    Zhang, Qianping
    Shen, Natalie
    Bai, Jinbing
    Luo, Xianwu
    Liu, Yanqun
    EXPERIMENTAL GERONTOLOGY, 2023, 177