Supranuclear Vertical Gaze Palsy in Movement Disorders

被引：0
作者：
Salari, Mehri [1 ]
Alikhani, Alireza [1 ]
Hojjati Pour, Fatemeh [2 ]
Etemadifar, Masoud [3 ]
机构：
[1] Shohada Tajrish Hosp, Funct Neurosurg Res Ctr, Shohada Tajrish Comprehens Neurosurg Ctr Excellenc, Tajrish Sq, Tehran 1989934148, Iran
[2] Shahid Beheshti Univ Med Sci, Student Res Comm, Fac Med, Tehran, Iran
[3] Isfahan Med Univ, Dept Neurosurg, Esfahan, Iran
来源：
NEURO-OPHTHALMOLOGY | 2025年 / 49卷 / 01期
关键词：
Parkinsonism; eye movement; tremor; ataxia; CREUTZFELDT-JAKOB-DISEASE; NIEMANN-PICK-DISEASE; CENTRAL-NERVOUS-SYSTEM; BRAIN-STEM ENCEPHALITIS; STIFF-PERSON SYNDROME; EYE-MOVEMENTS; WHIPPLES-DISEASE; WILSONS-DISEASE; CORTICOBASAL DEGENERATION; SPINOCEREBELLAR-ATAXIA;
D O I：
10.1080/01658107.2024.2379423
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Vertical gaze palsy, a neurological impairment affecting the upward and downward movement of the eyes, can be caused by various disorders. Understanding this phenomenon is essential for accurate diagnosis and effective management. This review aims to present a practical overview of vertical gaze palsy, its manifestation in various movement disorders, and the clinical relevance of such impairments. We did a thorough non-systematic search of the literature in PubMed with various keywords such as 'gaze palsy', 'vertical gaze palsy', 'gaze abnormality', and 'eye movement disorder'. Vertical gaze palsy can manifest in various disorders such as Parkinson's disease, atypical Parkinsonian syndromes, Niemann-Pick disease type C, Wilson's disease, Whipple's disease, prion disease, and several others. This comprehensive review elucidates the spectrum of movement disorders linked to vertical gaze palsy, exploring the specific ways it manifests and the complexities in diagnosing the condition. The list of movement disorders causing vertical gaze palsy is extremely wide, encompassing neurodegenerative, metabolic, infectious, autoimmune disorders, and intoxication with certain substances and specific medications. The differential diagnosis consists of various etiologies with heterogeneous presentations that may overlap and mimic each other. We hope that this paper will assist practitioners in managing the complex process of diagnosing a patient with vertical gaze palsy.
引用
收藏
页码：17 / 34
页数：18
相关论文
共 185 条
  • [1] Stiff-person syndrome (SPS) and anti-GAD-related CNS degenerations: Protean additions to the autoimmune central neuropathies
    Ali, Fatima
    Rowley, Merrill
    Jayakrishnan, Bindu
    Teuber, Suzanne
    Gershwin, M. Eric
    Mackay, Ian R.
    [J]. JOURNAL OF AUTOIMMUNITY, 2011, 37 (02) : 79 - 87
  • [2] Eye movements in patients with neurodegenerative disorders
    Anderson, Tim J.
    MacAskill, Michael R.
    [J]. NATURE REVIEWS NEUROLOGY, 2013, 9 (02) : 74 - 85
  • [3] Arias M., NEUROLOGIA
  • [4] Criteria for the diagnosis of corticobasal degeneration
    Armstrong, Melissa J.
    Litvan, Irene
    Lang, Anthony E.
    Bak, Thomas H.
    Bhatia, Kailash P.
    Borroni, Barbara
    Boxer, Adam L.
    Dickson, Dennis W.
    Grossman, Murray
    Hallett, Mark
    Josephs, Keith A.
    Kertesz, Andrew
    Lee, Suzee E.
    Miller, Bruce L.
    Reich, Stephen G.
    Riley, David E.
    Tolosa, Eduardo
    Troester, Alexander I.
    Vidailhet, Marie
    Weiner, William J.
    [J]. NEUROLOGY, 2013, 80 (05) : 496 - 503
  • [5] Visual signs and symptoms of multiple system atrophy
    Armstrong, Richard A.
    [J]. CLINICAL AND EXPERIMENTAL OPTOMETRY, 2014, 97 (06) : 483 - 491
  • [6] Barbero-Aznarez Pablo, 2022, Surg Neurol Int, V13, P477, DOI 10.25259/SNI_591_2022
  • [7] Clinical and radiological spectrum of Japanese encephalitis
    Basumatary, Lakshya J.
    Raja, D.
    Bhuyan, Dipu
    Das, Marami
    Goswami, Munindra
    Kayal, Ashok K.
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2013, 325 (1-2) : 15 - 21
  • [8] Clinical Spectrum of Kufor-Rakeb Syndrome in the Chilean Kindred with ATP13A2 Mutations
    Behrens, Maria I.
    Brueggemann, Norbert
    Chana, Pedro
    Venegas, Pablo
    Kaegi, Marianne
    Parrao, Teresa
    Orellana, Patricia
    Garrido, Cristian
    Rojas, Cecilia V.
    Hauke, Jan
    Hahnen, Eric
    Gonzalez, Rafael
    Seleme, Nicolas
    Fernandez, Veronica
    Schmidt, Alexander
    Binkofski, Ferdinand
    Koempf, Detlef
    Kubisch, Christian
    Hagenah, Johann
    Klein, Christine
    Ramirez, Alfredo
    [J]. MOVEMENT DISORDERS, 2010, 25 (12) : 1929 - 1937
  • [9] Accidental carbon monoxide poisoning presenting without a history of exposure: A case report
    Bennetto L.
    Powter L.
    Scolding N.J.
    [J]. Journal of Medical Case Reports, 2 (1)
  • [10] FAMILIAL CREUTZFELDT-JAKOB DISEASE (CODON-200 MUTATION) WITH SUPRANUCLEAR PALSY
    BERTONI, JM
    BROWN, P
    GOLDFARB, LG
    RUBENSTEIN, R
    GAJDUSEK, DC
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1992, 268 (17): : 2413 - 2415
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