Participation of Brahmi ( Bacopa monnieri L. ) plant in regulation of cancer

The history of Ayurveda shows a long-standing relationship between Bacopa monnieri L. (Brahmi) and human health, giving the plant a valuable source for developing nontoxic medications. Traditionally, Brahmi has been primarily used to treat insomnia, epilepsy, memory loss, and anxiety. This makes the plant a valuable resource for the safe development of alternative drugs. Research on B. monnieri 's biological effects has exploded in recent years, with the herb showing promise as a neuroprotective, memory -enhancing, and most importantly chemo-preventive and anti-neoplastic drug. In this particular context, a thorough review of the literature facilitates a profound comprehension of the roles played by particular bioactive compounds and the B. monnieri entire plant extract, which has different functional molecular pathways. Recent studies conducted by researchers report Brahmi as a promising neuroprotective, memory -enhancing, anti-neoplastic, and chemo-preventive agent. Each naturally occurring chemical component isolated from Bacopa monnieri leaf extract using various solvents exhibits strong anti -metastatic, anti-angiogenic, and antiproliferative properties on several cancer cells. This thorough analysis covering the recent research showing Brahmi 's anticancer effect will help one understand its role better and realize its potential as an effective anticancer drug. (c) 2024 SAAB. Published by Elsevier B.V. All rights reserved.