Asthma management, focused on the use of oral corticosteroids: the opinions of Italian asthmatic patients

被引:1
|
作者
Latorre, Manuela [1 ]
Rizzi, Angela [2 ]
Paggiaro, Pierluigi [3 ]
Baiardini, Ilaria [4 ]
Bagnasco, Diego [5 ,6 ]
Del Giacco, Stefano [7 ]
Lombardi, Carlo [8 ]
Patella, Vincenzo [9 ]
Nucera, Eleonora [2 ,10 ]
Parente, Roberta [11 ]
Paoletti, Giovanni [12 ,13 ]
Pini, Laura [14 ]
Ridolo, Erminia [15 ]
Senna, Gianenrico [16 ,17 ]
Blasi, Francesco [12 ,18 ,19 ,20 ]
Canonica, Giorgio Walter [13 ]
机构
[1] Nuovo Osped Apuano, Dept Med Specialties, Pulmonol Unit, Massa, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Med & Chirurg, UOSD Allergol & Immunol Clin, Rome, Italy
[3] Univ Pisa, Dept Surg Med Mol Biol & Crit Care, Pisa, Italy
[4] Univ Genoa, Dept Internal Med, Resp Clin, Genoa, Italy
[5] IRCCS Policlin San Martino, Clin Malattie Resp & Allergol, Genoa, Italy
[6] Univ Genoa, Dipartimento Med Interna DIMI, Genoa, Italy
[7] Univ Cagliari, Dept Med Sci & Publ Hlth, Unit Allergy & Clin Immunol, Cagliari, Italy
[8] Fdn Poliambulanza, Dept Unit Allergol & Resp Dis, Brescia, Italy
[9] Santa Maria Speranza Hosp, Dept Internal & Resp Med, Div Allergy & Clin Immunol, Salerno, Italy
[10] Univ Cattolica Sacro Cuore, Med & Chirurg Traslaz, Rome, Italy
[11] Univ Salerno, Dept Med, Div Allergy & Clin Immunol, Fisciano, Italy
[12] Humanitas Univ, Dept Biomed Sci, Milan, Italy
[13] IRCCS, Humanitas Clin & Res Ctr, Personalized Med Asthma & Allergy, Rozzano, Italy
[14] Univ Brescia, Dept Clin & Expt Sci, Spedali Civili Brescia, Brescia, Italy
[15] Univ Parma, Dept Med & Surg, Parma, Italy
[16] Univ Verona & Gen Hosp, Asthma Ctr, Verona, Italy
[17] Univ Verona & Gen Hosp, Allergy Unit, Verona, Italy
[18] Fdn IRCCS Ca Granda Osped Maggiore Policlin Milano, Internal Med Dept, Resp Unit, Milan, Italy
[19] Fdn IRCCS Ca Granda Osped Maggiore Policlin Milano, Cyst Fibrosis Ctr, Milan, Italy
[20] Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy
关键词
Asthma; survey; oral corticosteroids; patients' perceptions; management; quality of life; PERSPECTIVE; IMPACT; VALIDATION; RHINITIS; NETWORK;
D O I
10.1080/02770903.2024.2338863
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
ObjectivePatients' perceptions of asthma symptoms, and attitudes regarding diagnosis and management, can affect their ability to reach good asthma control. The aim of the study was to explore patients' perceptions of asthma management, with focus on treatment with oral corticosteroids (OCS).MethodsA DOXAPHARMA survey was conducted. A questionnaire with 46 multiple choice questions was completed by 50 patients with severe uncontrolled asthma, and 258 with mild-moderate controlled or partly controlled asthma. Participants were representative of Italian asthmatic patients-with medium age, long asthma duration, delayed diagnosis, poor asthma control, and frequent exacerbations.ResultsMany asthmatics reported inadequate pharmacologic treatment. The majority but not all patients regularly used ICS/LABA. Oral treatment was common, mainly with OCS, particularly in severe asthmatics. One-fourth of patients did not regularly use inhaled therapy, and adherence was poor, resulting in frequent OCS use to treat exacerbations, which were common in mild-moderate cases. Patients were fairly satisfied with asthma therapies, but many had concerns about long-term corticosteroid use. Patients complained about poor management of comorbidities associated with asthma and OCS use, but were generally satisfied with their patient/doctor relationships. Many patients failed to achieve optimal health-related quality of life (HRQoL), mainly those with severe asthma who used OCS treatment and emphasized how OCS therapy impacted QoL.ConclusionsThe survey results confirmed many problems related to mild-moderate and severe asthma management in Italy and highlighted the overuse of OCS rather than more effective and safe treatments, which had strong negative effects on HRQoL.
引用
收藏
页码:1294 / 1305
页数:12
相关论文
共 50 条
  • [41] Trends in oral corticosteroids use in severe asthma: a 14-year population-based study
    Sadatsafavi, Mohsen
    Khakban, Amir
    Tavakoli, Hamid
    Ehteshami-Afshar, Solmaz
    Lynd, Larry D.
    FitzGerald, J. Mark
    RESPIRATORY RESEARCH, 2021, 22 (01)
  • [42] Omalizumab in the management of oral corticosteroid-dependent IGE-mediated asthma patients
    Domingo, Christian
    Moreno, Amalia
    Jose Amengual, Ma
    Monton, Concepcion
    Suarez, David
    Pomares, Xavier
    CURRENT MEDICAL RESEARCH AND OPINION, 2011, 27 (01) : 45 - 53
  • [43] Trends in oral corticosteroids use in severe asthma: a 14-year population-based study
    Mohsen Sadatsafavi
    Amir Khakban
    Hamid Tavakoli
    Solmaz Ehteshami-Afshar
    Larry D. Lynd
    J. Mark FitzGerald
    Respiratory Research, 22
  • [44] Nationwide use of inhaled corticosteroids by South Korean asthma patients: an examination of the Health Insurance Review and Service database
    Choi, Joon Young
    Yoon, Hyoung Kyu
    Lee, Jae Ha
    Yoo, Kwang Ha
    Kim, Bo Yeon
    Bae, Hye Won
    Kim, Young Kyoon
    Rhee, Chin Kook
    JOURNAL OF THORACIC DISEASE, 2018, 10 (09) : 5405 - 5413
  • [45] Impact of adherence to asthma management guidelines in asthmatic patients: A primary healthcare center study
    Al-Musallam, Samia Salem
    Al-Jariky, Fotooh Ahmed
    Alhamdan, Asia Saad
    Ibrahim, Jassim Ma
    Ali, Seham Ahmed
    KUWAIT MEDICAL JOURNAL, 2008, 40 (03): : 216 - 220
  • [46] Adverse events profile of oral corticosteroids among asthma patients in the UK: cohort study with a nested case-control analysis
    Bloechliger, Marlene
    Reinau, Daphne
    Spoendlin, Julia
    Chang, Shih-Chen
    Kuhlbusch, Klaus
    Heaney, Liam G.
    Jick, Susan S.
    Meier, Christoph R.
    RESPIRATORY RESEARCH, 2018, 19
  • [47] Health care resource utilization and cost for asthma patients regularly treated with oral corticosteroids - a Swedish observational cohort study (PACEHR)
    Janson, Christer
    Lisspers, Karin
    Stallberg, Bjorn
    Johansson, Gunnar
    Telg, Gunilla
    Thuresson, Marcus
    Christensen, Helene Nordahl
    Larsson, Kjell
    RESPIRATORY RESEARCH, 2018, 19
  • [48] Effect of dupilumab on oral corticosteroid use in severe asthma patients with improving lung function
    Maspero, Jorge F.
    Halpin, David M. G.
    Jackson, David
    Hanania, Nicola A.
    Castro, Mario
    Domingo, Christian
    Daizadeh, Nadia
    Djandji, Michel
    Rowe, Paul
    Deniz, Yamo
    EUROPEAN RESPIRATORY JOURNAL, 2020, 56
  • [49] Expert consensus on oral corticosteroid use and tapering in severe asthma management
    Kim, Joo-Hee
    Kang, Noeul
    Kang, Sung-Yoon
    Sim, Da Woon
    Park, So-Young
    Park, Jong-Sook
    Lee, Hyun
    Jin, Hyun Jung
    Song, Woo-Jung
    Kim, So Ri
    Kim, Sang-Heon
    ALLERGY ASTHMA & RESPIRATORY DISEASE, 2025, 13 (01): : 12 - 21
  • [50] The use of corticosteroids in patients with COPD or asthma does not decrease lung squamous cell carcinoma
    Jian, Zhi-Hong
    Huang, Jing-Yang
    Lin, Frank Cheau-Feng
    Nfor, Oswald Ndi
    Jhang, Kai-Ming
    Ku, Wen-Yuan
    Ho, Chien-Chang
    Lung, Chia-Chi
    Pan, Hui-Hsien
    Liang, Yu-Chiu
    Wu, Ming-Fang
    Liaw, Yung-Po
    BMC PULMONARY MEDICINE, 2015, 15