Asthma management, focused on the use of oral corticosteroids: the opinions of Italian asthmatic patients

被引:1
|
作者
Latorre, Manuela [1 ]
Rizzi, Angela [2 ]
Paggiaro, Pierluigi [3 ]
Baiardini, Ilaria [4 ]
Bagnasco, Diego [5 ,6 ]
Del Giacco, Stefano [7 ]
Lombardi, Carlo [8 ]
Patella, Vincenzo [9 ]
Nucera, Eleonora [2 ,10 ]
Parente, Roberta [11 ]
Paoletti, Giovanni [12 ,13 ]
Pini, Laura [14 ]
Ridolo, Erminia [15 ]
Senna, Gianenrico [16 ,17 ]
Blasi, Francesco [12 ,18 ,19 ,20 ]
Canonica, Giorgio Walter [13 ]
机构
[1] Nuovo Osped Apuano, Dept Med Specialties, Pulmonol Unit, Massa, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Med & Chirurg, UOSD Allergol & Immunol Clin, Rome, Italy
[3] Univ Pisa, Dept Surg Med Mol Biol & Crit Care, Pisa, Italy
[4] Univ Genoa, Dept Internal Med, Resp Clin, Genoa, Italy
[5] IRCCS Policlin San Martino, Clin Malattie Resp & Allergol, Genoa, Italy
[6] Univ Genoa, Dipartimento Med Interna DIMI, Genoa, Italy
[7] Univ Cagliari, Dept Med Sci & Publ Hlth, Unit Allergy & Clin Immunol, Cagliari, Italy
[8] Fdn Poliambulanza, Dept Unit Allergol & Resp Dis, Brescia, Italy
[9] Santa Maria Speranza Hosp, Dept Internal & Resp Med, Div Allergy & Clin Immunol, Salerno, Italy
[10] Univ Cattolica Sacro Cuore, Med & Chirurg Traslaz, Rome, Italy
[11] Univ Salerno, Dept Med, Div Allergy & Clin Immunol, Fisciano, Italy
[12] Humanitas Univ, Dept Biomed Sci, Milan, Italy
[13] IRCCS, Humanitas Clin & Res Ctr, Personalized Med Asthma & Allergy, Rozzano, Italy
[14] Univ Brescia, Dept Clin & Expt Sci, Spedali Civili Brescia, Brescia, Italy
[15] Univ Parma, Dept Med & Surg, Parma, Italy
[16] Univ Verona & Gen Hosp, Asthma Ctr, Verona, Italy
[17] Univ Verona & Gen Hosp, Allergy Unit, Verona, Italy
[18] Fdn IRCCS Ca Granda Osped Maggiore Policlin Milano, Internal Med Dept, Resp Unit, Milan, Italy
[19] Fdn IRCCS Ca Granda Osped Maggiore Policlin Milano, Cyst Fibrosis Ctr, Milan, Italy
[20] Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy
关键词
Asthma; survey; oral corticosteroids; patients' perceptions; management; quality of life; PERSPECTIVE; IMPACT; VALIDATION; RHINITIS; NETWORK;
D O I
10.1080/02770903.2024.2338863
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
ObjectivePatients' perceptions of asthma symptoms, and attitudes regarding diagnosis and management, can affect their ability to reach good asthma control. The aim of the study was to explore patients' perceptions of asthma management, with focus on treatment with oral corticosteroids (OCS).MethodsA DOXAPHARMA survey was conducted. A questionnaire with 46 multiple choice questions was completed by 50 patients with severe uncontrolled asthma, and 258 with mild-moderate controlled or partly controlled asthma. Participants were representative of Italian asthmatic patients-with medium age, long asthma duration, delayed diagnosis, poor asthma control, and frequent exacerbations.ResultsMany asthmatics reported inadequate pharmacologic treatment. The majority but not all patients regularly used ICS/LABA. Oral treatment was common, mainly with OCS, particularly in severe asthmatics. One-fourth of patients did not regularly use inhaled therapy, and adherence was poor, resulting in frequent OCS use to treat exacerbations, which were common in mild-moderate cases. Patients were fairly satisfied with asthma therapies, but many had concerns about long-term corticosteroid use. Patients complained about poor management of comorbidities associated with asthma and OCS use, but were generally satisfied with their patient/doctor relationships. Many patients failed to achieve optimal health-related quality of life (HRQoL), mainly those with severe asthma who used OCS treatment and emphasized how OCS therapy impacted QoL.ConclusionsThe survey results confirmed many problems related to mild-moderate and severe asthma management in Italy and highlighted the overuse of OCS rather than more effective and safe treatments, which had strong negative effects on HRQoL.
引用
收藏
页码:1294 / 1305
页数:12
相关论文
共 50 条
  • [21] Preventing Emergency Department Visits and Hospitalizations for Asthma by Use of Oral Corticosteroids at Home: Are We Adhering to National Guidelines?
    Self, Timothy H.
    Chrisman, Cary R.
    Jacobs, Anna R.
    Vo, Ngan H.
    Winton, John C.
    JOURNAL OF ASTHMA, 2010, 47 (10) : 1123 - 1127
  • [22] Oral findings in pediatric patients with allergic rhinitis and asthma: a cohort study of an Italian setting
    Vitale, Marina Consuelo
    Pascadopoli, Maurizio
    Gallo, Simone
    Campanini, Marta
    Licari, Amelia
    Marseglia, Gian Luigi
    Scribante, Andrea
    JOURNAL OF CLINICAL PEDIATRIC DENTISTRY, 2023, 47 (06) : 51 - 58
  • [23] Blood eosinophil dose response to oral corticosteroids in a population of patients with severe asthma
    Austin, Daren
    Pouliquen, Isabelle
    Keene, Oliver
    Yancey, Steve
    EUROPEAN RESPIRATORY JOURNAL, 2016, 48
  • [24] Oral corticosteroids increase esophageal acid contact times in patients with stable asthma
    Lazenby, JP
    Guzzo, MR
    Harding, SM
    Patterson, PE
    Johnson, LF
    Bradley, LA
    CHEST, 2002, 121 (02) : 625 - 634
  • [25] Effects of the long acting beta agonist formoterol on asthma control in asthmatic patients using inhaled corticosteroids
    vanderMolen, T
    Postma, DS
    Turner, MO
    MeyboomdeJong, B
    Malo, JL
    Chapman, K
    Grossman, R
    deGraaff, CS
    Riemersma, RA
    Sears, MR
    THORAX, 1997, 52 (06) : 535 - 539
  • [26] Geographical differences in the use of oral corticosteroids in patients with severe asthma in Spain: heat map based on existing databases analyses
    Almonacid, Carlos
    Fitas, Eunice
    Sanchez-Covisa, Joaquin
    Gutierrez, Hector
    Rebollo, Pablo
    BMC PULMONARY MEDICINE, 2023, 23 (01)
  • [27] IMPACT OF 'THREE-IN-ONE' ASTHMA EDUCATION AND MANAGEMENT MODEL ON ASTHMA CONTROL IN ASTHMATIC PATIENTS
    Ma, Y.
    He, Q.
    RESPIROLOGY, 2011, 16 : 225 - 225
  • [28] Geographical differences in the use of oral corticosteroids in patients with severe asthma in Spain: heat map based on existing databases analyses
    Carlos Almonacid
    Eunice Fitas
    Joaquín Sánchez-Covisa
    Héctor Gutiérrez
    Pablo Rebollo
    BMC Pulmonary Medicine, 23
  • [29] Comparison of three different oral corticosteroids in steroid-dependent asthma patients
    Chanez, P
    Paradis, L
    DesRoches, A
    Paganin, F
    Bashir, M
    Godard, P
    Bousquet, J
    ALLERGY, 1996, 51 (11) : 850 - 851
  • [30] Economic Evaluation of the Use of FeNO for the Diagnosis and Management of Asthma Patients in Primary Care in Sweden
    Darba, Josep
    Ascanio, Meritxell
    Syk, Jorgen
    Alving, Kjell
    CLINICOECONOMICS AND OUTCOMES RESEARCH, 2021, 13 : 289 - 297