Self-Assembly of Peptides as an Alluring Approach toward Cancer Treatment and Imaging

被引:2
作者
Ghafoor, Muhammad Hamza [1 ,2 ]
Song, Ben-Li [1 ,2 ]
Zhou, Lei [1 ]
Qiao, Zeng-Ying [1 ,2 ]
Wang, Hao [1 ,2 ]
机构
[1] Natl Ctr Nanosci & Technol NCNST, CAS Ctr Excellence Nanosci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Ctr Mat Sci & Optoelect Engn, Beijing 100049, Peoples R China
来源
ACS BIOMATERIALS SCIENCE & ENGINEERING | 2024年 / 10卷 / 05期
基金
中国国家自然科学基金; 国家重点研发计划;
关键词
Peptide; self-assembly; cancer treatment; cancer imaging; CATION-PI INTERACTIONS; CYTOCHROME-C; DRUG-DELIVERY; CELL-CULTURE; HYDROGELS; BINDING; RECOGNITION; SYSTEMS; DESIGN; WATER;
D O I
10.1021/acsbiomaterials.4c00491
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Cancer is a severe threat to humans, as it is the second leading cause of death after cardiovascular diseases and still poses the biggest challenge in the world of medicine. Due to its higher mortality rates and resistance, it requires a more focused and productive approach to provide the solution for it. Many therapies promising to deliver favorable results, such as chemotherapy and radiotherapy, have come up with more negatives than positives. Therefore, a new class of medicinal solutions and a more targeted approach is of the essence. This review highlights the alluring properties, configurations, and self-assembly of peptide molecules which benefit the traditional approach toward cancer therapy while sparing the healthy cells in the process. As targeted drug delivery systems, self-assembled peptides offer a wide spectrum of conjugation, biocompatibility, degradability-controlled responsiveness, and biomedical applications, including cancer treatment and cancer imaging.
引用
收藏
页码:2841 / 2862
页数:22
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