Liposomes as Carriers of Bioactive Compounds in Human Nutrition

被引:15
作者
Rudzinska, Magdalena [1 ]
Grygier, Anna [1 ]
Knight, Geoffrey [1 ]
Kmiecik, Dominik [1 ]
机构
[1] Univ Life Sci, Fac Food Sci & Nutr, PL-60637 Poznan, Poland
关键词
liposomes; formation; encapsulation; bioactive compounds; extracts; antimicrobial; food components; stability; IN-VITRO; DELIVERY-SYSTEMS; ESSENTIAL OIL; COATED LIPOSOMES; NANO-LIPOSOMES; SHELF-LIFE; FISH-OIL; STABILITY; FOOD; ENCAPSULATION;
D O I
10.3390/foods13121814
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
This article provides an overview of the literature data on the role of liposomal structures and encapsulated substances in food technology and human nutrition. The paper briefly describes how liposomes are created and how they encapsulate food ingredients, which can either be individual compounds or plant extracts. Another very interesting application of liposomes is their use as antimicrobial carriers to protect food products from spoilage during storage. The encapsulation of food ingredients in liposomes can increase their bioavailability, which is particularly important for compounds with health-promoting properties but low bioavailability. Particular attention was paid to compounds such as phytosterols, which lower blood cholesterol levels but have very low absorption in the human body. In addition, consumer expectations and regulations for liposomes in food are discussed. To date, no in vivo human studies have been conducted to indicate which encapsulation methods give the best results for gastrointestinal effects and which food-added substances are most stable during food storage and processing. The paper identifies further lines of research that are needed before liposomes can be introduced into food.
引用
收藏
页数:20
相关论文
共 131 条
[1]   Synthesis of encapsulated fish oil using whey protein isolate to prevent the oxidative damage and cytotoxicity of titanium dioxide nanoparticles in rats [J].
Abdel-Wahhab, Mosaad A. ;
El-Nekeety, Aziza A. ;
Mohammed, Hagar E. ;
El-Messery, Tamer M. ;
Roby, Mohamed H. ;
Abdel-Aziem, Sekena H. ;
Hassan, Nabila S. .
HELIYON, 2021, 7 (11)
[2]   Relative expression of cholesterol transport-related proteins and inflammation markers through the induction of 7-ketosterol-mediated stress in Caco-2 cells [J].
Alemany, L. ;
Laparra, J. M. ;
Barbera, R. ;
Alegria, A. .
FOOD AND CHEMICAL TOXICOLOGY, 2013, 56 :247-253
[3]   Encapsulation-based technologies for bioactive compounds and their application in the food industry: A roadmap for food-derived functional and health-promoting ingredients [J].
Alu'datt, Muhammad H. ;
Alrosan, Mohammad ;
Gammoh, Sana ;
Tranchant, Carole C. ;
Alhamad, Mohammad N. ;
Rababah, Taha ;
Zghoul, Roa'a ;
Alzoubi, Haya ;
Ghatasheh, Salsabeel ;
Ghozlan, Kawther ;
Tan, Thuan-Chew .
FOOD BIOSCIENCE, 2022, 50
[4]   Storage stability, heat stability, controlled release and antifungal activity of liposomes as alternative fungal preservation agents [J].
Aslan, Mine ;
Ertas, Nilgun ;
Demir, M. Kursat .
FOOD BIOSCIENCE, 2023, 51
[5]   Antibacterial and anti-biofilm properties of cinnamaldehyde-loaded nanoliposomes against Listeria monocytogenes and Salmonella enteritidis adhered to stainless steel [J].
Baboli, Narges Hasanzadeh ;
Hosseini, Seyed Fakhreddin ;
Gharsallaoui, Adem .
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2023, 58 (10) :5275-5282
[6]   Antibacterial activities of polyphenols against foodborne pathogens and their application as antibacterial agents [J].
Bae, Ji-Yun ;
Seo, Yeon-Hee ;
Oh, Se-Wook .
FOOD SCIENCE AND BIOTECHNOLOGY, 2022, 31 (08) :985-997
[7]  
BANGHAM AD, 1963, ADV LIPID RES, V1, P65
[8]   Antifungal properties of phosphatidylcholine-oleic acid liposomes encapsulating garlic against environmental fungal in wheat bread [J].
Barreto Pinilla, Cristian Mauricio ;
Silveira Thys, Roberta Cruz ;
Brandelli, Adriano .
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2019, 293 :72-78
[9]   Impact of nisin producing culture and liposome-encapsulated nisin on ripening of Lactobacillus added-Cheddar cheese [J].
Benech, RO ;
Kheadr, EE ;
Lacroix, C ;
Fliss, I .
JOURNAL OF DAIRY SCIENCE, 2003, 86 (06) :1895-1909
[10]   In vivo comparison of various liposome formulations for cosmetic application [J].
Betz, G ;
Aeppli, A ;
Menshutina, N ;
Leuenberger, H .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2005, 296 (1-2) :44-54