A new 3,4-dinorsteroid from the marine sponge Cliona sp.

被引：0

作者：

Liu, Meng-Cheng ^{[1
]}

Liao, Xiao-Jian ^{[1
]}

Xing, Xi-Wen ^{[1
]}

Xu, Shi-Hai ^{[1
]}

Zhao, Bing-Xin ^{[1
]}

机构：

[1] Jinan Univ, Coll Chem & Mat Sci, Dept Chem, Guangzhou 510632, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2024年 / 26卷 / 10期

基金：

中国国家自然科学基金;

关键词：

Clionidae; marine sponge; Cliona; steroids; METABOLITES; STEROIDS; CELATA;

D O I：

10.1080/10286020.2024.2360114

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new steroid, 2a-oxa-2-oxo-5 beta-hydroxy-3,4-dinor-24-methylcholesta-22E-ene (1), together with 10 known ones (2-11), was isolated from the marine sponge Cliona sp. The structures of these compounds were determined by the spectroscopic methods (UV, IR, MS, and NMR) and X-ray diffraction analysis. Compound 1 was the third example of 3,4-dinorsteroid with a hemiketal at C-5 that was isolated from the natural source. In addition, the antibacterial activities of these compounds were also evaluated. However, none of them exhibited significant inhibition effects.

引用

页码：1254 / 1260

页数：7

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